Purine nucleoside kinases in mouse tissues and human lymphoid cells in culture

Ram P. Agarwal

doi:10.1016/0305-0491(81)90301-1

Purine nucleoside kinases in mouse tissues and human lymphoid cells in culture

Ram P. Agarwal

Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

1. 1. Purine nucleoside kinase activities (adenosine kinase, deoxyadenosine kinase and arabinosyl adenine kinase) in mouse tissues were in the following order: liver > kidney > heart > lung > brain > spleen > intestine. 2. 2. Ratios of deoxyadenosine or arabinosyl adenine kinase to adenosine kinase were significantly higher (10-200 fold) in human lymphoid cells than in mouse tissues. 3. 3. Leukocytes from T-cell acute lymphoblastic leukemic patients had 5-20 fold elevated adenosine deaminase as compared to normal T-cells.

Original language	English (US)
Pages (from-to)	595-599
Number of pages	5
Journal	Comparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume	70
Issue number	3
DOIs	https://doi.org/10.1016/0305-0491(81)90301-1
State	Published - 1981

ASJC Scopus subject areas

Biochemistry
Physiology
Molecular Biology

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AB - 1. 1. Purine nucleoside kinase activities (adenosine kinase, deoxyadenosine kinase and arabinosyl adenine kinase) in mouse tissues were in the following order: liver > kidney > heart > lung > brain > spleen > intestine. 2. 2. Ratios of deoxyadenosine or arabinosyl adenine kinase to adenosine kinase were significantly higher (10-200 fold) in human lymphoid cells than in mouse tissues. 3. 3. Leukocytes from T-cell acute lymphoblastic leukemic patients had 5-20 fold elevated adenosine deaminase as compared to normal T-cells.

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