Purine nucleoside kinases in mouse tissues and human lymphoid cells in culture

Ram P. Agarwal

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

1. 1. Purine nucleoside kinase activities (adenosine kinase, deoxyadenosine kinase and arabinosyl adenine kinase) in mouse tissues were in the following order: liver > kidney > heart > lung > brain > spleen > intestine. 2. 2. Ratios of deoxyadenosine or arabinosyl adenine kinase to adenosine kinase were significantly higher (10-200 fold) in human lymphoid cells than in mouse tissues. 3. 3. Leukocytes from T-cell acute lymphoblastic leukemic patients had 5-20 fold elevated adenosine deaminase as compared to normal T-cells.

Original languageEnglish (US)
Pages (from-to)595-599
Number of pages5
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume70
Issue number3
DOIs
StatePublished - 1981

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ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Molecular Biology

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