Purine metabolism in primitive erythrocytes

R. E. Parks, Phyllis R. Brown, Yung Chi Cheng, K. C. Agarwal, Chong M. Kong, R. P. Agarwal, Christopher C. Parks

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

1. 1. The activities of AMP kinase, GMP kinase, NDP kinase, PNPase and HGPRTase were determined in the erythrocytes of seal, eel, hagfish and dogfish. 2. 2. Erythrocytic NDP kinase activities were high and electrophoretically heterogeneous in all species examined. 3. 3. Patterns of nucleotide extracts of whole blood and erythrocytes in seal, sand dab, skate, hagfish, dogfish, nurse shark and stingray were similar when determined by high-pressure liquid chromatography. Patterns of the whole blood of eel and lemon shark, however, were strikingly different in containing large amounts of GDP and GTP.

Original languageEnglish (US)
Pages (from-to)355-364
Number of pages10
JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume45
Issue number2
DOIs
StatePublished - Jun 15 1973

Keywords

  • adenylate kinase
  • blood
  • erythrocytes
  • guanylate kinase
  • high-pressure liquid chromatography
  • Nucleoside diphosphokinase
  • Nucleotides
  • purine metabolism
  • purine nucleoside phosphorylase

ASJC Scopus subject areas

  • Medicine(all)

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