Pulsatile perfusion: Its effects on blood flow distribution in hypertrophied hearts

Tomas Salerno, H. M. Shizgal, A. R C Dobell

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Left ventricular hypertrophy was created in 15 pigs by banding the ascending aorta when they were young. The adult animals were placed on normothermic cardiopulmonary bypass and perfused with either nonpulsatile (two groups of pigs) or pulsatile (one group) flows. As long as the perfusion rate was maintained at 70 ml/kg/min, myocardial blood flow distribution, as determined by radioactive microspheres, was identical in the hearts with normal sinus rhythm and those with ventricular fibrillation irrespective of the type of perfusion. At low flow rates, however, subendocardial ischemia developed in all three groups, but was most severe in the fibrillating hearts, and was not reversed by pulsatile perfusion.

Original languageEnglish
Pages (from-to)559-563
Number of pages5
JournalAnnals of Thoracic Surgery
Volume27
Issue number6
StatePublished - Dec 1 1979
Externally publishedYes

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Pulsatile Flow
Swine
Perfusion
Left Ventricular Hypertrophy
Ventricular Fibrillation
Cardiopulmonary Bypass
Microspheres
Aorta
Ischemia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Pulsatile perfusion : Its effects on blood flow distribution in hypertrophied hearts. / Salerno, Tomas; Shizgal, H. M.; Dobell, A. R C.

In: Annals of Thoracic Surgery, Vol. 27, No. 6, 01.12.1979, p. 559-563.

Research output: Contribution to journalArticle

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