Pulmonary Mycobacterium Avium-Intracellulare Complex Infection in an Infant: A Silent and Coincidental Finding

Vishal Naik, Pui Ying Iroh Tam, William Gershan, Andrew Colin, Nadir Demirel

Research output: Contribution to journalArticle

Abstract

An 11-month-old healthy infant girl was noted to have left lower lobe (LLL) opacities on chest X-ray (CXR) after developing desaturations during an elective cochlear implant surgery. Repeat CXR 10 days later revealed hyperexpansion of the left lung and persistent LLL opacity. Chest computerized tomography revealed enlarged mediastinal lymph nodes, left mainstem bronchial obstruction, and nodular opacities. Bronchoscopic biopsy of the endobronchial tissue revealed multiple necrotizing granulomas and grew Mycobacterium avium-intracellulare, Streptococcus viridans, and Actinomyces odontolyticus. This case illustrates the potential for significant mediastinal lymphadenopathy, and endobronchial and parenchymal lesions caused by nontuberculous mycobacteria, which can present insidiously and without respiratory symptoms in otherwise healthy infants, despite advanced pulmonary disease.

Original languageEnglish (US)
Pages (from-to)257-259
Number of pages3
JournalPediatric, Allergy, Immunology, and Pulmonology
Volume30
Issue number4
DOIs
StatePublished - Dec 1 2017

Fingerprint

Mycobacterium avium-intracellulare Infection
Mycobacterium avium Complex
Thorax
Lung
X-Rays
Viridans Streptococci
Actinomyces
Nontuberculous Mycobacteria
Cochlear Implants
Granuloma
Lung Diseases
Lymph Nodes
Tomography
Biopsy

Keywords

  • endobronchial
  • mycobacteria
  • mycobacterium avium
  • nontuberculous
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Cite this

Pulmonary Mycobacterium Avium-Intracellulare Complex Infection in an Infant : A Silent and Coincidental Finding. / Naik, Vishal; Tam, Pui Ying Iroh; Gershan, William; Colin, Andrew; Demirel, Nadir.

In: Pediatric, Allergy, Immunology, and Pulmonology, Vol. 30, No. 4, 01.12.2017, p. 257-259.

Research output: Contribution to journalArticle

Naik, Vishal ; Tam, Pui Ying Iroh ; Gershan, William ; Colin, Andrew ; Demirel, Nadir. / Pulmonary Mycobacterium Avium-Intracellulare Complex Infection in an Infant : A Silent and Coincidental Finding. In: Pediatric, Allergy, Immunology, and Pulmonology. 2017 ; Vol. 30, No. 4. pp. 257-259.
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