Pulmonary embolism with bone fragments following vertebral body marrow infusion for tolerance induction

Luis A. Fernandez; Rita Romaguera; Ana L. Viciana; Phillip Ruiz; Andreas G. Tzakis; Camillo Ricordi

doi:10.1016/0963-6897(96)00026-7

Pulmonary embolism with bone fragments following vertebral body marrow infusion for tolerance induction

Luis A. Fernandez, Rita Romaguera, Ana L. Viciana, Phillip Ruiz, Andreas G. Tzakis, Camillo Ricordi

Surgery

Research output: Contribution to journal › Article

3 Scopus citations

Abstract

Protocols of donor bone marrow infusion for tolerance induction are receiving increasing attention in clinical trials of organ allotransplantation. We report pulmonary embolism with bone fragments following vertebral body marrow infusion in a recipient of a liver and intestinal transplant. Even though pulmonary embolism with bony microfragments has been widely described following bone marrow transplantation, the use of single, high-dose donor bone marrow infusion and/or multiple infusions currently under clinical investigation for induction of donor specific unresponsiveness, may warrant the implementation of additional steps in the vertebral body marrow processing technique to decrease or eliminate the component of bony microfragments in the final preparation.

Original language	English (US)
Pages (from-to)	513-516
Number of pages	4
Journal	Cell Transplantation
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/0963-6897(96)00026-7
State	Published - Jan 1 1996

Keywords

Bone fragments
Bone marrow
Cures pulmonary embolism
Tolerance
Vertebral body

ASJC Scopus subject areas

Cell Biology
Transplantation

Access to Document

10.1016/0963-6897(96)00026-7

Fingerprint Dive into the research topics of 'Pulmonary embolism with bone fragments following vertebral body marrow infusion for tolerance induction'. Together they form a unique fingerprint.

Cite this

@article{7aa6b5b817f54eb9b397bc41c6c18d54,

title = "Pulmonary embolism with bone fragments following vertebral body marrow infusion for tolerance induction",

abstract = "Protocols of donor bone marrow infusion for tolerance induction are receiving increasing attention in clinical trials of organ allotransplantation. We report pulmonary embolism with bone fragments following vertebral body marrow infusion in a recipient of a liver and intestinal transplant. Even though pulmonary embolism with bony microfragments has been widely described following bone marrow transplantation, the use of single, high-dose donor bone marrow infusion and/or multiple infusions currently under clinical investigation for induction of donor specific unresponsiveness, may warrant the implementation of additional steps in the vertebral body marrow processing technique to decrease or eliminate the component of bony microfragments in the final preparation.",

keywords = "Bone fragments, Bone marrow, Cures pulmonary embolism, Tolerance, Vertebral body",

author = "Fernandez, {Luis A.} and Rita Romaguera and Viciana, {Ana L.} and Phillip Ruiz and Tzakis, {Andreas G.} and Camillo Ricordi",

year = "1996",

month = jan,

day = "1",

doi = "10.1016/0963-6897(96)00026-7",

language = "English (US)",

volume = "5",

pages = "513--516",

journal = "Cell Transplantation",

issn = "0963-6897",

publisher = "Cognizant Communication Corporation",

number = "4",

}

TY - JOUR

T1 - Pulmonary embolism with bone fragments following vertebral body marrow infusion for tolerance induction

AU - Fernandez, Luis A.

AU - Romaguera, Rita

AU - Viciana, Ana L.

AU - Ruiz, Phillip

AU - Tzakis, Andreas G.

AU - Ricordi, Camillo

PY - 1996/1/1

Y1 - 1996/1/1

N2 - Protocols of donor bone marrow infusion for tolerance induction are receiving increasing attention in clinical trials of organ allotransplantation. We report pulmonary embolism with bone fragments following vertebral body marrow infusion in a recipient of a liver and intestinal transplant. Even though pulmonary embolism with bony microfragments has been widely described following bone marrow transplantation, the use of single, high-dose donor bone marrow infusion and/or multiple infusions currently under clinical investigation for induction of donor specific unresponsiveness, may warrant the implementation of additional steps in the vertebral body marrow processing technique to decrease or eliminate the component of bony microfragments in the final preparation.

AB - Protocols of donor bone marrow infusion for tolerance induction are receiving increasing attention in clinical trials of organ allotransplantation. We report pulmonary embolism with bone fragments following vertebral body marrow infusion in a recipient of a liver and intestinal transplant. Even though pulmonary embolism with bony microfragments has been widely described following bone marrow transplantation, the use of single, high-dose donor bone marrow infusion and/or multiple infusions currently under clinical investigation for induction of donor specific unresponsiveness, may warrant the implementation of additional steps in the vertebral body marrow processing technique to decrease or eliminate the component of bony microfragments in the final preparation.

KW - Bone fragments

KW - Bone marrow

KW - Cures pulmonary embolism

KW - Tolerance

KW - Vertebral body

UR - http://www.scopus.com/inward/record.url?scp=0029986219&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029986219&partnerID=8YFLogxK

U2 - 10.1016/0963-6897(96)00026-7

DO - 10.1016/0963-6897(96)00026-7

M3 - Article

C2 - 8800520

AN - SCOPUS:0029986219

VL - 5

SP - 513

EP - 516

JO - Cell Transplantation

JF - Cell Transplantation

SN - 0963-6897

IS - 4

ER -