Pulmonary edema with nifedipine in primary pulmonary hypertension

Anil K. Batra, Peter H. Segall, Tahir Ahmed

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Despite occasional case reports, vasodilator therapy of primary pulmonary hypertension remains unsatisfactory. Nifedipine, a calcium channel antagonist, has recently been recommended for the treatment of primary pulmonary hypertension. Transient mild side effects to this drug have been known. In this report we describe a case of primary pulmonary hypertension in whom oral nifedipine use was followed by fatal pulmonary edema. We suggest that nifedipine has the potential of causing life-threatening complications of pulmonary edema in patients with severe primary pulmonary hypertension, and in this condition it should be used cautiously.

Original languageEnglish (US)
Pages (from-to)161-163
Number of pages3
JournalRespiration
Volume47
Issue number3
DOIs
StatePublished - Jan 1 1985

Keywords

  • Nifedipine
  • Primary pulmonary hypertension
  • Pulmonary edema

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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