Psychosomatic factors in pruritus

Hong Liang Tey, Joanna Wallengren, Gil Yosipovitch

Research output: Contribution to journalComment/debate

47 Citations (Scopus)

Abstract

Pruritus and psyche are intricately and reciprocally related, with psychophysiological evidence and psychopathological explanations helping us to understand their complex association. Their interaction may be conceptualized and classified into 3 groups: pruritic diseases with psychiatric sequelae, pruritic diseases aggravated by psychosocial factors, and psychiatric disorders causing pruritus. Management of chronic pruritus is directed at treating the underlying causes and adopting a multidisciplinary approach to address the dermatologic, somatosensory, cognitive, and emotional aspects. Pharmcotherapeutic agents that are useful for chronic pruritus with comorbid depression and/or anxiety comprise selective serotonin reuptake inhibitors, mirtazapine, tricyclic antidepressants (amitriptyline and doxepin), and anticonvulsants (gabapentin, pregabalin); the role of neurokinin receptor-1 antagonists awaits verification. Antipsychotics are required for treating itch and formication associated with schizophrenia and delusion of parasitosis (including Morgellons disease).

Original languageEnglish (US)
Pages (from-to)31-40
Number of pages10
JournalClinics in Dermatology
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

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Pruritus
Morgellons Disease
Psychiatry
Neurokinin-1 Receptor Antagonists
Doxepin
Amitriptyline
Delusions
Paresthesia
Tricyclic Antidepressive Agents
Serotonin Uptake Inhibitors
Anticonvulsants
Antipsychotic Agents
Schizophrenia
Anxiety
Depression
Psychology

ASJC Scopus subject areas

  • Dermatology

Cite this

Psychosomatic factors in pruritus. / Tey, Hong Liang; Wallengren, Joanna; Yosipovitch, Gil.

In: Clinics in Dermatology, Vol. 31, No. 1, 01.01.2013, p. 31-40.

Research output: Contribution to journalComment/debate

Tey, Hong Liang ; Wallengren, Joanna ; Yosipovitch, Gil. / Psychosomatic factors in pruritus. In: Clinics in Dermatology. 2013 ; Vol. 31, No. 1. pp. 31-40.
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