Psychosocial factors and disease progression in cancer

Michael H Antoni, Susan Lutgendorf

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Psychosocial factors such as stress, personality, and social support relate to differences in disease progression in cancer patients. Neuroendocrine substances associated with psychosocial factors may regulate immune responses to cancer, as well as regulate the activity of oncogenic (cancer-causing) viruses, DNA-repair processes, and the expression in tumor cells of genes that may affect the tumor's growth and metastasis. Biobehavioral oncology research seeks to understand how these psychosocial factors, and interventions designed to modify them, become neurohormonal changes that alter cell signaling and tumor growth, viral oncogenesis, and immune responses. We review the empirical basis for psychosocial factors and biobehavioral processes in cancer progression and suggest future research.

Original languageEnglish
Pages (from-to)42-46
Number of pages5
JournalCurrent Directions in Psychological Science
Volume16
Issue number1
DOIs
StatePublished - Feb 1 2007

Fingerprint

Disease Progression
Psychology
Neoplasms
Growth
DNA Repair
Social Support
Personality
Carcinogenesis
Neoplasm Metastasis
Viruses
Research
Genes

Keywords

  • Oncogenesis
  • Psychoneuroimmunologic
  • Psychosocial
  • Tumor growth

ASJC Scopus subject areas

  • Psychology(all)

Cite this

Psychosocial factors and disease progression in cancer. / Antoni, Michael H; Lutgendorf, Susan.

In: Current Directions in Psychological Science, Vol. 16, No. 1, 01.02.2007, p. 42-46.

Research output: Contribution to journalArticle

@article{c6fdc1091e3a4605b5e802ec1ef5298d,
title = "Psychosocial factors and disease progression in cancer",
abstract = "Psychosocial factors such as stress, personality, and social support relate to differences in disease progression in cancer patients. Neuroendocrine substances associated with psychosocial factors may regulate immune responses to cancer, as well as regulate the activity of oncogenic (cancer-causing) viruses, DNA-repair processes, and the expression in tumor cells of genes that may affect the tumor's growth and metastasis. Biobehavioral oncology research seeks to understand how these psychosocial factors, and interventions designed to modify them, become neurohormonal changes that alter cell signaling and tumor growth, viral oncogenesis, and immune responses. We review the empirical basis for psychosocial factors and biobehavioral processes in cancer progression and suggest future research.",
keywords = "Oncogenesis, Psychoneuroimmunologic, Psychosocial, Tumor growth",
author = "Antoni, {Michael H} and Susan Lutgendorf",
year = "2007",
month = "2",
day = "1",
doi = "10.1111/j.1467-8721.2007.00472.x",
language = "English",
volume = "16",
pages = "42--46",
journal = "Current Directions in Psychological Science",
issn = "0963-7214",
publisher = "SAGE Publications Inc.",
number = "1",

}

TY - JOUR

T1 - Psychosocial factors and disease progression in cancer

AU - Antoni, Michael H

AU - Lutgendorf, Susan

PY - 2007/2/1

Y1 - 2007/2/1

N2 - Psychosocial factors such as stress, personality, and social support relate to differences in disease progression in cancer patients. Neuroendocrine substances associated with psychosocial factors may regulate immune responses to cancer, as well as regulate the activity of oncogenic (cancer-causing) viruses, DNA-repair processes, and the expression in tumor cells of genes that may affect the tumor's growth and metastasis. Biobehavioral oncology research seeks to understand how these psychosocial factors, and interventions designed to modify them, become neurohormonal changes that alter cell signaling and tumor growth, viral oncogenesis, and immune responses. We review the empirical basis for psychosocial factors and biobehavioral processes in cancer progression and suggest future research.

AB - Psychosocial factors such as stress, personality, and social support relate to differences in disease progression in cancer patients. Neuroendocrine substances associated with psychosocial factors may regulate immune responses to cancer, as well as regulate the activity of oncogenic (cancer-causing) viruses, DNA-repair processes, and the expression in tumor cells of genes that may affect the tumor's growth and metastasis. Biobehavioral oncology research seeks to understand how these psychosocial factors, and interventions designed to modify them, become neurohormonal changes that alter cell signaling and tumor growth, viral oncogenesis, and immune responses. We review the empirical basis for psychosocial factors and biobehavioral processes in cancer progression and suggest future research.

KW - Oncogenesis

KW - Psychoneuroimmunologic

KW - Psychosocial

KW - Tumor growth

UR - http://www.scopus.com/inward/record.url?scp=33947204130&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33947204130&partnerID=8YFLogxK

U2 - 10.1111/j.1467-8721.2007.00472.x

DO - 10.1111/j.1467-8721.2007.00472.x

M3 - Article

AN - SCOPUS:33947204130

VL - 16

SP - 42

EP - 46

JO - Current Directions in Psychological Science

JF - Current Directions in Psychological Science

SN - 0963-7214

IS - 1

ER -