Psychoneuroimmunology of health and long survival with HIV/AIDS: Questionnaires, semistructured interviews, and laboratory findings

George F. Solomon, Gail Ironson, Elizabeth G. Balbin, Mary Ann Fletcher

Research output: Contribution to journalArticle

Abstract

A 5-year research project has compared psychologically and immunologically long survivors with AIDS as well as HIV+ persons who have remained healthy in the face of very low CD4+ cell counts with a group of HIV+ persons without symptomatic AIDS and CD4 counts between 150 and 500 mm3. Long survival is characterized by a collaborative relationship with physician, and religious/spiritual coping. Optimism characterizes healthy HIV+ persons with low CD4 counts, whose health may be protected by the unusual preservation of normal levels of natural killer cell cytotoxicity (NKCC). Refusal to perceive disease as imminently fatal and coping well with loss correlate positively with NKCC and negatively with viral load; toleration of loss correlates positively with CD4 count. Both specially designed self-administered tests and rated semistructured interviews are useful in discerning psychosocial factors related to health and long survival and their biological correlates.

Original languageEnglish (US)
Pages (from-to)27-30
Number of pages4
JournalInternational Congress Series
Volume1241
Issue numberC
DOIs
StatePublished - Sep 1 2002

Keywords

  • AIDS
  • HIV
  • Health with low CD4
  • Long survival
  • Psychoneuroimmunology

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Psychoneuroimmunology of health and long survival with HIV/AIDS: Questionnaires, semistructured interviews, and laboratory findings'. Together they form a unique fingerprint.

  • Cite this