Psychiatric Disorders in the Parents of Autistic Individuals

JOSEPH PIVEN, GARY A. CHASE, REBECCA LANDA, MARYANN WZOREK, JEANNE GAYLE, DELORES CLOUD, SUSAN FOLSTEIN

Research output: Contribution to journalArticlepeer-review

157 Scopus citations

Abstract

Eighty-one parents of 42 autistic probands and 34 parents of 18 Down syndrome probands were examined using a semistructured, investigator-based version of the Schedule for Affective Disorders and Schizophrenia Lifetime Version to estimate the lifetime risk of psychiatric disorder. The lifetime prevalence rate of anxiety disorder was significantly greater in parents of autistic probands than in parents of Down syndrome probands. The lifetime prevalence rate of major depressive disorder, while not significantly different in cases and controls, may be high in the parents of autistic probands (27%) in comparison with populations rates.

Original languageEnglish (US)
Pages (from-to)471-478
Number of pages8
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume30
Issue number3
DOIs
StatePublished - 1991

Keywords

  • Anxiety disorder
  • Autism
  • Genetics
  • Major depressive disorder
  • Stress

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

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