Psychiatric comorbidities in epilepsy: Should they be considered in the classification of epileptic disorders?

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24 Scopus citations

Abstract

The prevalence of psychiatric comorbidities is relatively high in people with epilepsy (PWE), as one in three patients will have experienced a psychiatric disorder in the course of their life. The new definition of epilepsy recognizes these comorbidities as part of the seizure disorder, which need to be recognized and treated together with the actual epileptic seizures. Psychiatric comorbidities have a complex relation with epilepsy, being associated with a negative course of the seizure disorder, worse tolerance of pharmacotherapy with AEDs, development of iatrogenic psychiatric complications from pharmacologic and surgical treatments, and increased mortality risks. Given their negative impact at several levels of the lives of PWE, should psychiatric comorbidities be included in a classification of the epilepsies? This question is addressed in this article. This article is part of a Special Issue entitled “The new approach to classification: Rethinking cognition and behavior in epilepsy”.

Original languageEnglish (US)
Pages (from-to)306-308
Number of pages3
JournalEpilepsy and Behavior
Volume64
DOIs
StatePublished - Nov 1 2016

Keywords

  • Generalized anxiety disorder
  • Major depressive disorder
  • Temporal lobe epilepsy
  • Treatment-resistant epilepsy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Behavioral Neuroscience

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