Abstract
Psoriasis is one of the most common chronic skin diseases, and unprecedented increases in the elderly population will make diagnosis and management of geriatric psoriasis increasingly important. Management of psoriasis in the elderly requires consideration of several important factors. Many commonly prescribed drugs can precipitate psoriasis or aggravate pre-existing psoriasis. In addition, elderly patients are at increased risk of adverse drug reactions due to polypharmacy, adverse drug-drug interactions, adverse drug-disease interactions, incorrect use of medication and concomitant comorbidities. Psoriasis is a highly variable disease that requires individualized treatment. The major classes of topical medications include topical corticosteroids, coal tar preparations, calcipotriol, tazarotene and salicylic acid. Phototherapy, including narrowband ultraviolet B, photochemotherapy, psoralen ultraviolet A and excimer laser treatment, can be effective in properly selected patients. Systemic therapy for psoriasis in the elderly should be reserved for severe, extensive cases that have failed to respond to topical treatment, and may include methotrexate, systemic retinoids and immunotherapy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 611-623 |
| Number of pages | 13 |
| Journal | Aging Health |
| Volume | 3 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 1 2007 |
| Externally published | Yes |
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Keywords
- Calcipotriol
- Carticosteroids
- Coal tar
- Compliance
- Drug-induced psoriasis
- Elderly
- Immunotherapy
- Methotrexate
- Phototherapy
- Psoriasis
- Topical
ASJC Scopus subject areas
- Medicine(all)
- Geriatrics and Gerontology
Cite this
Psoriasis in the elderly. / Dawn, Aerlyn G.; Dawn, Marianne Edwards; Yosipovitch, Gil.
In: Aging Health, Vol. 3, No. 5, 01.10.2007, p. 611-623.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Psoriasis in the elderly
AU - Dawn, Aerlyn G.
AU - Dawn, Marianne Edwards
AU - Yosipovitch, Gil
PY - 2007/10/1
Y1 - 2007/10/1
N2 - Psoriasis is one of the most common chronic skin diseases, and unprecedented increases in the elderly population will make diagnosis and management of geriatric psoriasis increasingly important. Management of psoriasis in the elderly requires consideration of several important factors. Many commonly prescribed drugs can precipitate psoriasis or aggravate pre-existing psoriasis. In addition, elderly patients are at increased risk of adverse drug reactions due to polypharmacy, adverse drug-drug interactions, adverse drug-disease interactions, incorrect use of medication and concomitant comorbidities. Psoriasis is a highly variable disease that requires individualized treatment. The major classes of topical medications include topical corticosteroids, coal tar preparations, calcipotriol, tazarotene and salicylic acid. Phototherapy, including narrowband ultraviolet B, photochemotherapy, psoralen ultraviolet A and excimer laser treatment, can be effective in properly selected patients. Systemic therapy for psoriasis in the elderly should be reserved for severe, extensive cases that have failed to respond to topical treatment, and may include methotrexate, systemic retinoids and immunotherapy.
AB - Psoriasis is one of the most common chronic skin diseases, and unprecedented increases in the elderly population will make diagnosis and management of geriatric psoriasis increasingly important. Management of psoriasis in the elderly requires consideration of several important factors. Many commonly prescribed drugs can precipitate psoriasis or aggravate pre-existing psoriasis. In addition, elderly patients are at increased risk of adverse drug reactions due to polypharmacy, adverse drug-drug interactions, adverse drug-disease interactions, incorrect use of medication and concomitant comorbidities. Psoriasis is a highly variable disease that requires individualized treatment. The major classes of topical medications include topical corticosteroids, coal tar preparations, calcipotriol, tazarotene and salicylic acid. Phototherapy, including narrowband ultraviolet B, photochemotherapy, psoralen ultraviolet A and excimer laser treatment, can be effective in properly selected patients. Systemic therapy for psoriasis in the elderly should be reserved for severe, extensive cases that have failed to respond to topical treatment, and may include methotrexate, systemic retinoids and immunotherapy.
KW - Calcipotriol
KW - Carticosteroids
KW - Coal tar
KW - Compliance
KW - Drug-induced psoriasis
KW - Elderly
KW - Immunotherapy
KW - Methotrexate
KW - Phototherapy
KW - Psoriasis
KW - Topical
UR - http://www.scopus.com/inward/record.url?scp=35848935182&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35848935182&partnerID=8YFLogxK
U2 - 10.2217/1745509X.3.5.611
DO - 10.2217/1745509X.3.5.611
M3 - Review article
AN - SCOPUS:35848935182
VL - 3
SP - 611
EP - 623
JO - Aging Health
JF - Aging Health
SN - 1745-509X
IS - 5
ER -