Pseudotumor Cerebri from Cranial Venous Obstruction

Byron L. Lam, Norman J. Schatz, Joel S. Glaser, Brian C. Bowen

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

Dural sinus hypertension from cerebral venous outflow impairment is a cause of pseudotumor cerebri. The authors documented six such patients: two with unilateral neck dissection, one with surgical ligation of the dominant sigmoid sinus, two with thrombosed central intravenous catheterization, and one with dural sinus thrombosis. The site of cerebral venous outflow obstruction was variable and identified in three patients with computed tomography, conventional magnetic resonance imaging, magnetic resonance angiography, and/or angiography. Magnetic resonance angiography used in two patients characterized the venous flow pattern and identified the site of obstruction, confirming magnetic resonance angiography as an effective noninvasive blood flow technique in diagnosing and following these patients. Three patients were treated successfully with medical therapy and one patient with optic nerve fenestration. The two patients with thrombosed central venous catheters had serious systemic illnesses and suffered permanent visual loss.

Original languageEnglish (US)
Pages (from-to)706-712
Number of pages7
JournalOphthalmology
Volume99
Issue number5
DOIs
StatePublished - 1992

ASJC Scopus subject areas

  • Ophthalmology

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