Pruritus

An overview. What drives people to scratch an itch?

Michael Joseph Lavery, Michael Owen Kinney, Hideki Mochizuki, John Craig, Gil Yosipovitch

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Pruritus is a common complaint associated with many conditions. It negatively impacts sleep, quality of life, and mortality. Itch is transmitted along both histaminergic and non-histaminergic pathways with a complex interplay between keratinocytes, immune cells and cutaneous neurons. Individuals who present with pruritus should undergo a thorough assessment, especially those over 65 years old, to exclude underlying malignancy. Treatment no longer consists of antihistamines alone. Physicians now have an array of therapies in their armamentarium, to help alleviate this distressing symptom.

Original languageEnglish (US)
Pages (from-to)167-173
Number of pages7
JournalUlster Medical Journal
Volume85
Issue number3
StatePublished - Sep 1 2016
Externally publishedYes

Fingerprint

Pruritus
Histamine Antagonists
Keratinocytes
Sleep
Quality of Life
Physicians
Neurons
Skin
Mortality
Therapeutics
Neoplasms
Drive

Keywords

  • Histaminergic
  • Immune cells
  • Keratinocytes
  • Malignancy
  • Neurobiology
  • Neuropathic
  • Non-histaminergic
  • Pruritus
  • Unmyelinated C-nerve fibers

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Pruritus : An overview. What drives people to scratch an itch? / Lavery, Michael Joseph; Kinney, Michael Owen; Mochizuki, Hideki; Craig, John; Yosipovitch, Gil.

In: Ulster Medical Journal, Vol. 85, No. 3, 01.09.2016, p. 167-173.

Research output: Contribution to journalArticle

Lavery, Michael Joseph ; Kinney, Michael Owen ; Mochizuki, Hideki ; Craig, John ; Yosipovitch, Gil. / Pruritus : An overview. What drives people to scratch an itch?. In: Ulster Medical Journal. 2016 ; Vol. 85, No. 3. pp. 167-173.
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