Proximal femoral allografts in revision total hip arthroplasty

Patients with total hip arthroplasty (THA) and aseptic loosening associated with severe bone deficiency were treated with freeze-dried bone allografts of the proximal one-third of the femur. Twenty-two of the first 25 patients were available for review with an average follow-up period of 28 months. Significant functional improvement was obtained in 16 patients (73%). The following complications occurred with allograft revisions: dislocation, wound hematoma, joint instability, non-union, implant failure, and acetabular loosening. Nine patients required additional surgical procedures. There have been no infections or rapid lysis indicative of an allograft rejection phenomenon. The 73% success at the two-year postoperative interval of incorporation of freeze-dried allografts for salvage situations has been encouraging. However, the long-term durability of these grafts is not known and will require further follow-up study.