Protein Secretion Systems

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

All proteins are synthesized within membrane-bound cells. However, to be functional a substantial number of proteins must be transported through membranes. Cells possess dedicated export systems that first identify and then transport (or translocate) specific proteins through membranes. Defective functioning of these protein translocation systems are implicated in a number of human diseases.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages482-491
Number of pages10
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
DOIs
StatePublished - Feb 27 2013

Keywords

  • Endoplasmic reticulum
  • Golgi apparatus
  • Lipid bilayer
  • Protein misfolding
  • Ribosomes
  • Signal sequence
  • Translocation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)
  • Agricultural and Biological Sciences(all)

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