Prostate cancer prevention with 5 alpha-reductase inhibitors

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations


Testosterone gets converted into the more potent 5-[alpha]- dihydrotestosterone by 5-[alpha]- reductase. dihydrotestosterone (DHT) controls prostate mitotic activity and potentially prostate carcinogenesis. Interventions that inhibit 5-[alpha]-reductase have potential as preventive agents for prostate cancer.

Original languageEnglish (US)
Title of host publicationClinical Cancer Prevention
EditorsHans-Jorg Senn, Florian Otto
Number of pages6
StatePublished - Feb 7 2011
Externally publishedYes

Publication series

NameRecent Results in Cancer Research
ISSN (Print)0080-0015

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Parekh, D. J. (2011). Prostate cancer prevention with 5 alpha-reductase inhibitors. In H-J. Senn, & F. Otto (Eds.), Clinical Cancer Prevention (pp. 109-114). (Recent Results in Cancer Research; Vol. 188).