Abstract
This study was undertaken to examine the effects of intrauterine infection and preterm labor on the amniotic fluid concentrations of prostaglandins in women with premature rupture of the membranes. Amniotic fluid was obtained from four groups of patients with premature rupture of the membranes: group 1, patients without labor or infection; group 2, patients with labor but without infection; group 3, patients with an intra-amniotic infection but without labor; group 4, patients with both infection and labor. Prostaglandins E2 and F(2α) were measured by radioimmunoassays. Preterm labor, in the absence of infection, was not associated with significant increases in amniotic fluid concentrations of prostaglandins. Women with preterm labor and intra-amniotic infections had higher amniotic fluid concentrations of prostaglandins than women with preterm labor in the absence of infection or women with intra-amniotic infection in the absence of labor. These observations are compatible with the participation of prostaglandins in the mechanism of onset of preterm labor associated with intra-amniotic infection.
Original language | English |
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Pages (from-to) | 1461-1467 |
Number of pages | 7 |
Journal | American Journal of Obstetrics and Gynecology |
Volume | 157 |
Issue number | 6 |
State | Published - Dec 1 1987 |
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ASJC Scopus subject areas
- Medicine(all)
- Obstetrics and Gynecology
Cite this
Prostaglandin concentrations in amniotic fluid of women with intra-amniotic infection and preterm labor. / Romero, R.; Emamian, M.; Wan, M.; Quintero, R.; Hobbins, J. C.; Mitchell, M. D.
In: American Journal of Obstetrics and Gynecology, Vol. 157, No. 6, 01.12.1987, p. 1461-1467.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prostaglandin concentrations in amniotic fluid of women with intra-amniotic infection and preterm labor
AU - Romero, R.
AU - Emamian, M.
AU - Wan, M.
AU - Quintero, R.
AU - Hobbins, J. C.
AU - Mitchell, M. D.
PY - 1987/12/1
Y1 - 1987/12/1
N2 - This study was undertaken to examine the effects of intrauterine infection and preterm labor on the amniotic fluid concentrations of prostaglandins in women with premature rupture of the membranes. Amniotic fluid was obtained from four groups of patients with premature rupture of the membranes: group 1, patients without labor or infection; group 2, patients with labor but without infection; group 3, patients with an intra-amniotic infection but without labor; group 4, patients with both infection and labor. Prostaglandins E2 and F(2α) were measured by radioimmunoassays. Preterm labor, in the absence of infection, was not associated with significant increases in amniotic fluid concentrations of prostaglandins. Women with preterm labor and intra-amniotic infections had higher amniotic fluid concentrations of prostaglandins than women with preterm labor in the absence of infection or women with intra-amniotic infection in the absence of labor. These observations are compatible with the participation of prostaglandins in the mechanism of onset of preterm labor associated with intra-amniotic infection.
AB - This study was undertaken to examine the effects of intrauterine infection and preterm labor on the amniotic fluid concentrations of prostaglandins in women with premature rupture of the membranes. Amniotic fluid was obtained from four groups of patients with premature rupture of the membranes: group 1, patients without labor or infection; group 2, patients with labor but without infection; group 3, patients with an intra-amniotic infection but without labor; group 4, patients with both infection and labor. Prostaglandins E2 and F(2α) were measured by radioimmunoassays. Preterm labor, in the absence of infection, was not associated with significant increases in amniotic fluid concentrations of prostaglandins. Women with preterm labor and intra-amniotic infections had higher amniotic fluid concentrations of prostaglandins than women with preterm labor in the absence of infection or women with intra-amniotic infection in the absence of labor. These observations are compatible with the participation of prostaglandins in the mechanism of onset of preterm labor associated with intra-amniotic infection.
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M3 - Article
C2 - 3480691
AN - SCOPUS:0023547901
VL - 157
SP - 1461
EP - 1467
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
SN - 0002-9378
IS - 6
ER -