Prospects for malaria elimination in non-Amazonian regions of Latin America

Sócrates Herrera, Martha Lucia Quiñones, Juan Pablo Quintero, Vladimir Corredor, Douglas O. Fuller, Julio Cesar Mateus, Jose E. Calzada, Juan B. Gutierrez, Alejandro Llanos, Edison Soto, Clara Menendez, Yimin Wu, Pedro Alonso, Gabriel Carrasquilla, Mary Galinski, John C. Beier, Myriam Arévalo-Herrera

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Latin America contributes 1-1.2 million clinical malaria cases to the global malaria burden of about 300 million per year. In 21 malaria endemic countries, the population at risk in this region represents less than 10% of the total population exposed worldwide. Factors such as rapid deforestation, inadequate agricultural practices, climate change, political instability, and both increasing parasite drug resistance and vector resistance to insecticides contribute to malaria transmission. Recently, several malaria endemic countries have experienced a significant reduction in numbers of malaria cases. This is most likely due to actions taken by National Malaria Control Programs (NMCP) with the support from international funding agencies. We describe here the research strategies and activities to be undertaken by the Centro Latino Americano de Investigación en Malaria (CLAIM), a new research center established for the non-Amazonian region of Latin America by the National Institute of Allergy and Infectious Diseases (NIAID). Throughout a network of countries in the region, initially including Colombia, Guatemala, Panama, and Peru, CLAIM will address major gaps in our understanding of changing malaria epidemiology, vector biology and control, and clinical malaria mainly due to Plasmodium vivax. In close partnership with NMCPs, CLAIM seeks to conduct research on how and why malaria is decreasing in many countries of the region as a basis for developing and implementing new strategies that will accelerate malaria elimination.

Original languageEnglish (US)
Pages (from-to)315-323
Number of pages9
JournalActa Tropica
Volume121
Issue number3
DOIs
StatePublished - Mar 2012

Keywords

  • Anopheles mosquitoes
  • Epidemiology
  • Latin America
  • Malaria
  • Malaria elimination
  • Malaria pathogenesis
  • Non-Amazon regions
  • Plasmodium falciparum
  • Plasmodium vivax
  • Vector control

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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