Prospective assessment of patient reported urinary continence after radical prostatectomy

John T. Wei, Rodney L. Dunn, Robert Marcovich, James E. Montie, Martin G. Sanda

Research output: Contribution to journalArticle

216 Citations (Scopus)

Abstract

Purpose: Reported urinary continence rates after radical prostatectomy vary. Although modifications of radical prostatectomy meant to improve outcome, such as nerve sparing or bladder neck preservation, are in widespread use, to our knowledge evidence to support these practices based on patient report is scant. We evaluated the potential effects of nerve sparing and bladder neck preservation on urinary continence after radical prostatectomy, and assessed the impact of various urinary continence definitions on the observed outcome. Materials and Methods: We prospectively evaluated a cohort of men with prostate cancer who elected surgery with and without nerve sparing, and bladder neck preservation as primary therapy. A total of 482 men completed a brief urinary continence questionnaire preoperatively and postoperatively at a median followup of 18 months. Urinary continence was followed prospectively using the questionnaire and patient reported urinary continence recovery was based on 3 definitions of continence. Results: Median time to continence recovery based on patient reporting was significantly shorter in the nerve sparing than in the nonnerve sparing group when continence was defined as no urinary leakage (5.3 versus 10.9 months, p < 0.01). A multivariate model controlling for baseline factors revealed that significant predictors of continence outcome were preoperative continence, patient age, nerve sparing and the interaction of nerve sparing with age (p < 0.05). The definition of urinary continence also affected outcome. Conclusions: The nerve sparing technique of radical prostatectomy was associated with improved recovery of urinary continence in an age dependent manner, whereas bladder neck preservation was not beneficial. Patient age and the sensitivity of the incontinence definitions, as reflected by the associated variable rates of preoperative baseline incontinence, are significant contexts for interpreting urinary function data after radical prostatectomy. These factors may partially explain the variation in continence rates in the literature.

Original languageEnglish (US)
Pages (from-to)744-748
Number of pages5
JournalJournal of Urology
Volume164
Issue number3 I
StatePublished - Sep 2000
Externally publishedYes

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Prostatectomy
Urinary Bladder
Prostatic Neoplasms
Surveys and Questionnaires
Therapeutics

Keywords

  • Outcome assessment (health care)
  • Prostate
  • Prostatectomy
  • Quality of life
  • Urinary incontinence

ASJC Scopus subject areas

  • Urology

Cite this

Wei, J. T., Dunn, R. L., Marcovich, R., Montie, J. E., & Sanda, M. G. (2000). Prospective assessment of patient reported urinary continence after radical prostatectomy. Journal of Urology, 164(3 I), 744-748.

Prospective assessment of patient reported urinary continence after radical prostatectomy. / Wei, John T.; Dunn, Rodney L.; Marcovich, Robert; Montie, James E.; Sanda, Martin G.

In: Journal of Urology, Vol. 164, No. 3 I, 09.2000, p. 744-748.

Research output: Contribution to journalArticle

Wei, JT, Dunn, RL, Marcovich, R, Montie, JE & Sanda, MG 2000, 'Prospective assessment of patient reported urinary continence after radical prostatectomy', Journal of Urology, vol. 164, no. 3 I, pp. 744-748.
Wei, John T. ; Dunn, Rodney L. ; Marcovich, Robert ; Montie, James E. ; Sanda, Martin G. / Prospective assessment of patient reported urinary continence after radical prostatectomy. In: Journal of Urology. 2000 ; Vol. 164, No. 3 I. pp. 744-748.
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