Proportional assist ventilation in infants

Andreas Schulze, Eduardo Bancalari

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Proportional assist ventilation and respiratory mechanical unloading is a new mode of respiratory assistance that produces similar gas exchange with lower airway pressures than conventional ventilation in infants. This is achieved by tailoring the ventilator pressure contour to the specific derangements in lung mechanics and by a near perfect synchronization with the infant's own inspiratory effort. In contrast to conventional ventilation, PAV only amplifies the effect on ventilation of the spontaneous respiratory effort and relies on the subject's respiratory control. Whether PAV will reduce the incidence of acute complications and chronic pulmonary sequelae in infants needs to be evaluated in randomized controlled trials.

Original languageEnglish (US)
Pages (from-to)561-578
Number of pages18
JournalClinics in Perinatology
Volume28
Issue number3
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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