Prophylaxis of venous thromboembolism in the US: Improving hospital performance

Steven L. Cohn

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Venous thromboembolism (VTE) prevention has been recognized as the most important practice for improving patient safety in hospitals. To be effective, VTE prophylaxis must be appropriately prescribed with respect to type, dose and duration. Large-scale studies of medical discharge records have highlighted low rates of appropriate thromboprophylaxis in hospitalized medical patients, especially those with cancer or severe lung disease. Lack of prophylaxis and an insufficient duration are the most common forms of inappropriate prophylaxis. Multifaceted, active, quality improvement initiatives have been developed and shown to successfully increase the appropriate prescribing of VTE prophylaxis in patients at risk. By increasing the use of appropriate VTE prophylaxis in at-risk patients, the disease burden of hospital-acquired VTE and its resulting complications can be reduced.

Original languageEnglish (US)
Pages (from-to)1437-1445
Number of pages9
JournalJournal of Thrombosis and Haemostasis
Issue number9
StatePublished - 2009


  • Clinical guidelines
  • Deep vein thrombosis
  • Prophylaxis
  • Pulmonary embolism
  • Quality improvement
  • Venous thromboembolism

ASJC Scopus subject areas

  • Hematology


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