Prolonged intrahepatic cholestasis secondary to acute hepatitis A

S. C. Gordon, K. R. Reddy, L. Schiff, Eugene R Schiff

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Viral hepatitis characterized by prolonged cholestasis has not been associated with a specific serologic marker. We report the cases of six patients presenting with a clinical syndrome typical of cholestatic hepatitis who were subsequently found to have acute hepatitis A. Usual features include pruritus, fever, diarrhea, and weight loss with serum bilirubin levels greater than 10 mg/dL, and a clinical course lasting at least 12 weeks. All patients recovered completely without sequelae. Knowledge of this unusual manifestation of hepatitis A may help avoid potentially invasive procedures involved in the evaluation of suspected obstructive jaundice and facilitate appropriate immunoprophylactic measures.

Original languageEnglish
Pages (from-to)635-637
Number of pages3
JournalAnnals of Internal Medicine
Volume101
Issue number5
StatePublished - Dec 1 1984

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Intrahepatic Cholestasis
Hepatitis A
Hepatitis
Obstructive Jaundice
Cholestasis
Pruritus
Bilirubin
Weight Loss
Diarrhea
Fever
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Prolonged intrahepatic cholestasis secondary to acute hepatitis A. / Gordon, S. C.; Reddy, K. R.; Schiff, L.; Schiff, Eugene R.

In: Annals of Internal Medicine, Vol. 101, No. 5, 01.12.1984, p. 635-637.

Research output: Contribution to journalArticle

Gordon, SC, Reddy, KR, Schiff, L & Schiff, ER 1984, 'Prolonged intrahepatic cholestasis secondary to acute hepatitis A', Annals of Internal Medicine, vol. 101, no. 5, pp. 635-637.
Gordon, S. C. ; Reddy, K. R. ; Schiff, L. ; Schiff, Eugene R. / Prolonged intrahepatic cholestasis secondary to acute hepatitis A. In: Annals of Internal Medicine. 1984 ; Vol. 101, No. 5. pp. 635-637.
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