Prolonged elevation of luteinizing hormone (LH) after intranasal administration of an analog of LH releasing hormone

D. Gonzalez-Barcena, A. J. Kastin, D. S. Schalch, D. H. Coy, A. V. Schally

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

[D Leu 6, desGly NH 2 10] LH RH ethylamide, an analog of the luteinizing hormone releasing hormone (LH RH), was administered by intranasal spray or tube to 18 healthy men. A significant release of LH occurred within 15 minutes and was sustained for as long as 12 hours in what appeared to be a biphasic response. Both the spray and rhinyl tube were shown to be effective methods for releasing LH by intranasal administration of the LH RH analog.

Original languageEnglish (US)
Pages (from-to)1246-1249
Number of pages4
JournalUnknown Journal
Volume27
Issue number11
DOIs
StatePublished - 1976
Externally publishedYes

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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