Progressive systemic sclerosis in a family

Robert G. Gray, Roy D. Altman, Robert G. Gray, Roy D. Altman

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Progressive systemic sclerosis (PSS) developed in a 6‐year‐old boy and in his 38‐year‐old mother 9 years later. Both parent and child had Raynaud's phenomenon, integumental sclerosis, and pulmonary involvement, but they differed in other aspects of their disease. Previous descriptions of the familial occurrence of PSS are reviewed and compared to the present case reports. Environmental and genetic factors of possible etiologic significance are discussed.

Original languageEnglish (US)
Pages (from-to)35-41
Number of pages7
JournalArthritis & Rheumatism
Issue number1
StatePublished - Jan 1 1977

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)


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