Abstract
Congenital central nervous system infection with cytomegalovirus (CMV) usually results in a nonprogressive encephalopathy. Ninety percent of patients with clinically apparent infections at birth have a permanent neurological disability. It has been suggested that some infants may have persistent infection manifested by progressive encephalopathy during infancy. In the present case, clinical and pathological findings suggest the reactivation of a prior intrauterine CMV infection in a child with human T-lymphotrophic virus type III (HTLV-III) infection. The presence of HTLV-III may have reduced the immune surveillance of this infant, allowing the CMV to reactivate.
| Original language | English |
|---|---|
| Pages (from-to) | 255-257 |
| Number of pages | 3 |
| Journal | Child's Nervous System |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| State | Published - Oct 1 1987 |
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Keywords
- AIDS
- Congenital infection
- Cytomegalovirus
- Encephalopathy
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology
Cite this
Progressive cytomegalovirus encephalopathy following congenital infection in an infant with acquired immunodeficiency syndrome. / Curless, Richard G.; Scott, Gwendolyn B; Judith Post, M.; Gregorios, Jocelyn B.
In: Child's Nervous System, Vol. 3, No. 4, 01.10.1987, p. 255-257.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Progressive cytomegalovirus encephalopathy following congenital infection in an infant with acquired immunodeficiency syndrome
AU - Curless, Richard G.
AU - Scott, Gwendolyn B
AU - Judith Post, M.
AU - Gregorios, Jocelyn B.
PY - 1987/10/1
Y1 - 1987/10/1
N2 - Congenital central nervous system infection with cytomegalovirus (CMV) usually results in a nonprogressive encephalopathy. Ninety percent of patients with clinically apparent infections at birth have a permanent neurological disability. It has been suggested that some infants may have persistent infection manifested by progressive encephalopathy during infancy. In the present case, clinical and pathological findings suggest the reactivation of a prior intrauterine CMV infection in a child with human T-lymphotrophic virus type III (HTLV-III) infection. The presence of HTLV-III may have reduced the immune surveillance of this infant, allowing the CMV to reactivate.
AB - Congenital central nervous system infection with cytomegalovirus (CMV) usually results in a nonprogressive encephalopathy. Ninety percent of patients with clinically apparent infections at birth have a permanent neurological disability. It has been suggested that some infants may have persistent infection manifested by progressive encephalopathy during infancy. In the present case, clinical and pathological findings suggest the reactivation of a prior intrauterine CMV infection in a child with human T-lymphotrophic virus type III (HTLV-III) infection. The presence of HTLV-III may have reduced the immune surveillance of this infant, allowing the CMV to reactivate.
KW - AIDS
KW - Congenital infection
KW - Cytomegalovirus
KW - Encephalopathy
UR - http://www.scopus.com/inward/record.url?scp=0023488818&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023488818&partnerID=8YFLogxK
U2 - 10.1007/BF00274063
DO - 10.1007/BF00274063
M3 - Article
C2 - 2825996
AN - SCOPUS:0023488818
VL - 3
SP - 255
EP - 257
JO - Child's Nervous System
JF - Child's Nervous System
SN - 0256-7040
IS - 4
ER -