To the Editor: Many of the patients studied by Ruskin et al. (September 11 issue) may have had compromised cerebral and cardiac vessels. If one grants that this type of human experimentation is likely to produce some information of benefit to medical science, are we really gaining much of importance that could not be obtained in a less hazardous manner? Even if the information gained is great, does the gain justify inducing hypoperfusion states in compromised patients? I was reassured to note that patients who became unconscious quickly underwent cardioversion or defibrillation. Still, this sort of experimentation was formerly restricted. . .
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