Prognosis of Patients with Bilateral Macular Drusen

William E. Smiddy; Stuart L. Fine

doi:10.1016/S0161-6420(84)34309-3

Prognosis of Patients with Bilateral Macular Drusen

William E. Smiddy, Stuart L. Fine

Research output: Contribution to journal › Article › peer-review

163 Scopus citations

Abstract

Of 71 patients with only bilateral macular drusen, 8 eyes in 7 patients (9.9%) developed exudative maculopathy over an average follow-up of 4.3 years (14.5% cumulative risk). Severe visual loss due to exudative maculopathy occurred in 7 eyes of 6 patients (8.5% for a 5-year cumulative risk of 12.7%. Features of the drusen were analyzed, but only the association with focal hyperpigmentation (P < 0.001) and more than minimal drusen confluence (P < 0.05) were statistically significant. Older patients had more severe drusen. Photostress test delay did not correlate with visual acuity, age, or severity of drusen.

Original language	English (US)
Pages (from-to)	271-277
Number of pages	7
Journal	Ophthalmology
Volume	91
Issue number	3
DOIs	https://doi.org/10.1016/S0161-6420(84)34309-3
State	Published - Jan 1 1984
Externally published	Yes

Keywords

choroidal neovascularization
drusen
photostress test
risk factors
senile macular degeneration

ASJC Scopus subject areas

Ophthalmology

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title = "Prognosis of Patients with Bilateral Macular Drusen",

abstract = "Of 71 patients with only bilateral macular drusen, 8 eyes in 7 patients (9.9%) developed exudative maculopathy over an average follow-up of 4.3 years (14.5% cumulative risk). Severe visual loss due to exudative maculopathy occurred in 7 eyes of 6 patients (8.5% for a 5-year cumulative risk of 12.7%. Features of the drusen were analyzed, but only the association with focal hyperpigmentation (P < 0.001) and more than minimal drusen confluence (P < 0.05) were statistically significant. Older patients had more severe drusen. Photostress test delay did not correlate with visual acuity, age, or severity of drusen.",

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doi = "10.1016/S0161-6420(84)34309-3",

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T1 - Prognosis of Patients with Bilateral Macular Drusen

AU - Smiddy, William E.

AU - Fine, Stuart L.

PY - 1984/1/1

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N2 - Of 71 patients with only bilateral macular drusen, 8 eyes in 7 patients (9.9%) developed exudative maculopathy over an average follow-up of 4.3 years (14.5% cumulative risk). Severe visual loss due to exudative maculopathy occurred in 7 eyes of 6 patients (8.5% for a 5-year cumulative risk of 12.7%. Features of the drusen were analyzed, but only the association with focal hyperpigmentation (P < 0.001) and more than minimal drusen confluence (P < 0.05) were statistically significant. Older patients had more severe drusen. Photostress test delay did not correlate with visual acuity, age, or severity of drusen.

AB - Of 71 patients with only bilateral macular drusen, 8 eyes in 7 patients (9.9%) developed exudative maculopathy over an average follow-up of 4.3 years (14.5% cumulative risk). Severe visual loss due to exudative maculopathy occurred in 7 eyes of 6 patients (8.5% for a 5-year cumulative risk of 12.7%. Features of the drusen were analyzed, but only the association with focal hyperpigmentation (P < 0.001) and more than minimal drusen confluence (P < 0.05) were statistically significant. Older patients had more severe drusen. Photostress test delay did not correlate with visual acuity, age, or severity of drusen.

KW - choroidal neovascularization

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KW - photostress test

KW - risk factors

KW - senile macular degeneration

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Prognosis of Patients with Bilateral Macular Drusen

Abstract

Keywords

ASJC Scopus subject areas

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