PROGESTERONE AND GLUCOCORTICOID INTERACTIONS WITH RECEPTOR IN BREAST CANCER CELLS IN LONG‐TERM TISSUE CULTURE

Marc Lippman, Karen Huff, Gail Bolan

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Using the human cell line MCF 7, it was concluded that measurement of progesterone receptor in the presence of glucocorticoid binding sites, such as corticosteroid binding globulin or glucocorticoid receptor, can be readily accomplished with either R 5020 or progesterone, provided that unlabeled glucocorticoids are added to the assay tubes to saturate the sites for which glucocorticoids and progesterone both compete.

Original languageEnglish (US)
Pages (from-to)101-115
Number of pages15
JournalAnnals of the New York Academy of Sciences
Volume286
Issue number1
DOIs
StatePublished - Mar 1977

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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