Procuring organ donors as a health investment

How much should we be willing to spend?

John Mendeloff, Kilkon Ko, Mark S. Roberts, Margaret M Byrne, Mary Amanda Dew

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Background. This paper examines the benefits and costs that accrue when a cadaveric organ donor is procured. We estimate the cost per quality-adjusted life year (QALY) for donor procurement. Our objective was not only to see whether organ procurement is a "good" health investment, but also to clarify how much it is worth spending to obtain additional donors. Methods. We calculated the average number of kidney, heart, and liver transplants that a typical cadaveric donor generates. Relying primarily on reviewing the published literature, we estimated for each organ type the average number of QALYs that transplants add and the average medical costs they generate. We multiplied per organ benefits and costs by the number of organs from the typical donor, and summed the results to calculate the cost per QALY from procuring an additional donor. We conducted extensive sensitivity analyses of the assumptions. Results. Our central estimate indicates that the typical donor generates about 13 QALYs at an added medical cost of about $214,000, a cost of approximately $16,000 per QALY. Our high estimate is approximately $57,000. Conclusions. The implications of these findings depend upon how we choose to value QALYs. Most analysts agree that a figure of $100,000 is reasonable. At this value, the benefit obtained from one added donor would be $1.3 million (13 × $100,000) while the medical costs would be $214,000. The implication is that we should be willing to spend up to $1,086,000 ($1.3 million - $214,000) to obtain one more donor.

Original languageEnglish
Pages (from-to)1704-1710
Number of pages7
JournalTransplantation
Volume78
Issue number12
DOIs
StatePublished - Dec 27 2004

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Quality-Adjusted Life Years
Tissue Donors
Health
Costs and Cost Analysis
Cost-Benefit Analysis
Transplants
Tissue and Organ Procurement
Kidney
Liver

Keywords

  • Donor
  • Economic analysis
  • Procurement
  • Quality-adjusted life year

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Procuring organ donors as a health investment : How much should we be willing to spend? / Mendeloff, John; Ko, Kilkon; Roberts, Mark S.; Byrne, Margaret M; Dew, Mary Amanda.

In: Transplantation, Vol. 78, No. 12, 27.12.2004, p. 1704-1710.

Research output: Contribution to journalArticle

Mendeloff, John ; Ko, Kilkon ; Roberts, Mark S. ; Byrne, Margaret M ; Dew, Mary Amanda. / Procuring organ donors as a health investment : How much should we be willing to spend?. In: Transplantation. 2004 ; Vol. 78, No. 12. pp. 1704-1710.
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