Primary structure of bovine cerebellum GTP-binding protein G39 and its effect on the adenylate cyclase system

Yu A. Ovchinnikov, V. Z. Slepak, A. N. Pronin, A. B. Shlensky, N. B. Levina, V. L. Voeikov, V. M. Lipkin

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The primary structure of bovine cerebellum GTP-binding protein α-subunit, protein G39 was determined by parallel analysis of the protein amino acid sequence and the corresponding cDNA nucleotide sequence. The protein consists of 354 amino acid residues and has a molecular mass of 40064 Da. High homology between G39 and other G-proteins, especially rat brain Go was shown. An assumption is made that certain brain adenylate cyclase system properties are determined by the presence of G39.

Original languageEnglish (US)
Pages (from-to)91-95
Number of pages5
JournalFEBS letters
Volume226
Issue number1
DOIs
StatePublished - Dec 21 1987
Externally publishedYes

Keywords

  • (Bovine cerebellum)
  • Adenylate cyclase
  • Amino acid sequence
  • cDNA cloning
  • GTP-binding protein
  • Nucleotide sequence

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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    Ovchinnikov, Y. A., Slepak, V. Z., Pronin, A. N., Shlensky, A. B., Levina, N. B., Voeikov, V. L., & Lipkin, V. M. (1987). Primary structure of bovine cerebellum GTP-binding protein G39 and its effect on the adenylate cyclase system. FEBS letters, 226(1), 91-95. https://doi.org/10.1016/0014-5793(87)80557-4