Primary neuroendocrine carcinoma of the breast: report of 2 cases and literature review

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Neuroendocrine tumors of the breast are very rare accounting for less than 0.1% of all breast cancers and less than 1% of all neuroendocrine tumors. Focal neuroendocrine differentiation can be found in different histologic types of breast carcinoma including in situ and invasive ductal or invasive lobular. However, primary neuroendocrine carcinoma of the breast requires the expression of neuroendocrine markers in more than 50% of the cell population, the presence of ductal carcinoma in situ, and the absence of clinical evidence of concurrent primary neuroendocrine carcinoma of any other organ. Reports discussing the imaging characteristics of this rare carcinoma in different breast imaging modalities are scarce. We present 2 cases of primary neuroendocrine carcinoma of the breast for which mammography, ultrasound, and magnetic resonance imaging findings and pathology findings are described. A review of the medical literature on this particular topic was performed, and the results are presented.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalRadiology Case Reports
Volume12
Issue number1
DOIs
StatePublished - Mar 1 2017

    Fingerprint

Keywords

  • Breast
  • Carcinoma
  • Mammogram
  • MRI
  • Neuroendocrine
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this