Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection

Mehdi Mirsaeidi, P. Tabarsi, M. O. Edrissian, M. Amiri, P. Farnia, S. D. Mansouri, M. R. Masjedi, A. A. Velayati

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Primary multi-drug resistant extrapulmonary tuberculosis is an uncommon form of the disease, but it seems that by increasing the number drug resistant tuberculosis around the world, the number of cases of primary multidrug resistant tuberculosis with extrapulmonary presentation also is going to rise. In this report, we describe a 19-year old, HIV negative man with primary multi-drug resistant TB lymphadenitis, presented with cervical lymphadenopathy and sinus discharge at the site of involved lymph nodes. The Acid Fast Bacilli (AFB) smear of sputum was negative but the AFB smear of discharged fluid as well as the excisional biopsy of the lymph nodes confirmed the M. tuberculosis infection. The patient underwent the treatment with a combination of isoniazide, clofazimine, pyrazinamide, ofloxacin and amikacin with promising results. By increasing the number of drug resistant tuberculosis patients around the world, appropriate diagnosis and treatment of different presentations of the disease need a special attention.

Original languageEnglish (US)
Pages (from-to)244-247
Number of pages4
JournalMonaldi Archives for Chest Disease - Pulmonary Series
Volume61
Issue number4
StatePublished - Oct 2004
Externally publishedYes

Fingerprint

Multidrug-Resistant Tuberculosis
Lymphadenitis
HIV Infections
Bacillus
Lymph Nodes
Clofazimine
Pyrazinamide
Acids
Ofloxacin
Amikacin
Sputum
Tuberculosis
HIV
Biopsy
Therapeutics
Infection
Pharmaceutical Preparations

Keywords

  • HIV antibodies
  • Iran
  • Lymphadenitis
  • Multidrug-resistant
  • Tuberculosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine

Cite this

Mirsaeidi, M., Tabarsi, P., Edrissian, M. O., Amiri, M., Farnia, P., Mansouri, S. D., ... Velayati, A. A. (2004). Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection. Monaldi Archives for Chest Disease - Pulmonary Series, 61(4), 244-247.

Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection. / Mirsaeidi, Mehdi; Tabarsi, P.; Edrissian, M. O.; Amiri, M.; Farnia, P.; Mansouri, S. D.; Masjedi, M. R.; Velayati, A. A.

In: Monaldi Archives for Chest Disease - Pulmonary Series, Vol. 61, No. 4, 10.2004, p. 244-247.

Research output: Contribution to journalArticle

Mirsaeidi, M, Tabarsi, P, Edrissian, MO, Amiri, M, Farnia, P, Mansouri, SD, Masjedi, MR & Velayati, AA 2004, 'Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection', Monaldi Archives for Chest Disease - Pulmonary Series, vol. 61, no. 4, pp. 244-247.
Mirsaeidi, Mehdi ; Tabarsi, P. ; Edrissian, M. O. ; Amiri, M. ; Farnia, P. ; Mansouri, S. D. ; Masjedi, M. R. ; Velayati, A. A. / Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection. In: Monaldi Archives for Chest Disease - Pulmonary Series. 2004 ; Vol. 61, No. 4. pp. 244-247.
@article{706da38b512645ee8855c584f0e7bb83,
title = "Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection",
abstract = "Primary multi-drug resistant extrapulmonary tuberculosis is an uncommon form of the disease, but it seems that by increasing the number drug resistant tuberculosis around the world, the number of cases of primary multidrug resistant tuberculosis with extrapulmonary presentation also is going to rise. In this report, we describe a 19-year old, HIV negative man with primary multi-drug resistant TB lymphadenitis, presented with cervical lymphadenopathy and sinus discharge at the site of involved lymph nodes. The Acid Fast Bacilli (AFB) smear of sputum was negative but the AFB smear of discharged fluid as well as the excisional biopsy of the lymph nodes confirmed the M. tuberculosis infection. The patient underwent the treatment with a combination of isoniazide, clofazimine, pyrazinamide, ofloxacin and amikacin with promising results. By increasing the number of drug resistant tuberculosis patients around the world, appropriate diagnosis and treatment of different presentations of the disease need a special attention.",
keywords = "HIV antibodies, Iran, Lymphadenitis, Multidrug-resistant, Tuberculosis",
author = "Mehdi Mirsaeidi and P. Tabarsi and Edrissian, {M. O.} and M. Amiri and P. Farnia and Mansouri, {S. D.} and Masjedi, {M. R.} and Velayati, {A. A.}",
year = "2004",
month = "10",
language = "English (US)",
volume = "61",
pages = "244--247",
journal = "Monaldi Archives for Chest Disease",
issn = "1122-0643",
publisher = "Fondazione Salvatore Maugeri",
number = "4",

}

TY - JOUR

T1 - Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection

AU - Mirsaeidi, Mehdi

AU - Tabarsi, P.

AU - Edrissian, M. O.

AU - Amiri, M.

AU - Farnia, P.

AU - Mansouri, S. D.

AU - Masjedi, M. R.

AU - Velayati, A. A.

PY - 2004/10

Y1 - 2004/10

N2 - Primary multi-drug resistant extrapulmonary tuberculosis is an uncommon form of the disease, but it seems that by increasing the number drug resistant tuberculosis around the world, the number of cases of primary multidrug resistant tuberculosis with extrapulmonary presentation also is going to rise. In this report, we describe a 19-year old, HIV negative man with primary multi-drug resistant TB lymphadenitis, presented with cervical lymphadenopathy and sinus discharge at the site of involved lymph nodes. The Acid Fast Bacilli (AFB) smear of sputum was negative but the AFB smear of discharged fluid as well as the excisional biopsy of the lymph nodes confirmed the M. tuberculosis infection. The patient underwent the treatment with a combination of isoniazide, clofazimine, pyrazinamide, ofloxacin and amikacin with promising results. By increasing the number of drug resistant tuberculosis patients around the world, appropriate diagnosis and treatment of different presentations of the disease need a special attention.

AB - Primary multi-drug resistant extrapulmonary tuberculosis is an uncommon form of the disease, but it seems that by increasing the number drug resistant tuberculosis around the world, the number of cases of primary multidrug resistant tuberculosis with extrapulmonary presentation also is going to rise. In this report, we describe a 19-year old, HIV negative man with primary multi-drug resistant TB lymphadenitis, presented with cervical lymphadenopathy and sinus discharge at the site of involved lymph nodes. The Acid Fast Bacilli (AFB) smear of sputum was negative but the AFB smear of discharged fluid as well as the excisional biopsy of the lymph nodes confirmed the M. tuberculosis infection. The patient underwent the treatment with a combination of isoniazide, clofazimine, pyrazinamide, ofloxacin and amikacin with promising results. By increasing the number of drug resistant tuberculosis patients around the world, appropriate diagnosis and treatment of different presentations of the disease need a special attention.

KW - HIV antibodies

KW - Iran

KW - Lymphadenitis

KW - Multidrug-resistant

KW - Tuberculosis

UR - http://www.scopus.com/inward/record.url?scp=18044372610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18044372610&partnerID=8YFLogxK

M3 - Article

VL - 61

SP - 244

EP - 247

JO - Monaldi Archives for Chest Disease

JF - Monaldi Archives for Chest Disease

SN - 1122-0643

IS - 4

ER -