Primary lymphoma of the internal auditory canal. Case report and review of the literature

Simon I. Angeli, Bernard J. Poletti, Derald E. Brackmann, Joseph N. Carberry, John E. Xenellis, William E. Hitselberger

Research output: Contribution to journalArticle

20 Scopus citations


We report a rare case of a primary intracranial B cell lymphoma originating in the internal auditory canal. The clinical manifestations were indistinguishable from those of other, more common tumors of the same region. We achieved total gross tumor removal with preservation of the facial nerve. A detailed histologic examination and a systemic workup confirmed the primary nature of this tumor. To our knowledge, this is the second case reported in the literature of a primary malignant lymphoma originating in the internal auditory canal. This is the first instance that includes immunohistochemical and cytometric studies of fresh tissue. We discuss the management of primary lymphomas of the central nervous system, with special emphasis on their association with acquired immunodeficiency syndrome and other immune system diseases. Awareness of primary central nervous system lymphomas is important, since a greater occurrence of these rare tumors in the cerebellopontine angle is probable in the future.

Original languageEnglish (US)
Pages (from-to)17-21
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Issue number1
StatePublished - Jan 1 1998



  • Central nervous system lymphoma
  • Cerebellopontine angle tumor
  • DNA flow cytometry
  • Immunohistochemistry
  • Translabyrinthine craniotomy

ASJC Scopus subject areas

  • Otorhinolaryngology

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