Primary lymphoma of the internal auditory canal. Case report and review of the literature

Simon I Angeli, Bernard J. Poletti, Derald E. Brackmann, Joseph N. Carberry, John E. Xenellis, William E. Hitselberger

Research output: Contribution to journalArticle

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Abstract

We report a rare case of a primary intracranial B cell lymphoma originating in the internal auditory canal. The clinical manifestations were indistinguishable from those of other, more common tumors of the same region. We achieved total gross tumor removal with preservation of the facial nerve. A detailed histologic examination and a systemic workup confirmed the primary nature of this tumor. To our knowledge, this is the second case reported in the literature of a primary malignant lymphoma originating in the internal auditory canal. This is the first instance that includes immunohistochemical and cytometric studies of fresh tissue. We discuss the management of primary lymphomas of the central nervous system, with special emphasis on their association with acquired immunodeficiency syndrome and other immune system diseases. Awareness of primary central nervous system lymphomas is important, since a greater occurrence of these rare tumors in the cerebellopontine angle is probable in the future.

Original languageEnglish
Pages (from-to)17-21
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume107
Issue number1
StatePublished - Jan 29 1998
Externally publishedYes

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Lymphoma
Central Nervous System
Neoplasms
Acoustic Neuroma
Immune System Diseases
Facial Nerve
B-Cell Lymphoma
Acquired Immunodeficiency Syndrome

Keywords

  • Central nervous system lymphoma
  • Cerebellopontine angle tumor
  • DNA flow cytometry
  • Immunohistochemistry
  • Translabyrinthine craniotomy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Angeli, S. I., Poletti, B. J., Brackmann, D. E., Carberry, J. N., Xenellis, J. E., & Hitselberger, W. E. (1998). Primary lymphoma of the internal auditory canal. Case report and review of the literature. Annals of Otology, Rhinology and Laryngology, 107(1), 17-21.

Primary lymphoma of the internal auditory canal. Case report and review of the literature. / Angeli, Simon I; Poletti, Bernard J.; Brackmann, Derald E.; Carberry, Joseph N.; Xenellis, John E.; Hitselberger, William E.

In: Annals of Otology, Rhinology and Laryngology, Vol. 107, No. 1, 29.01.1998, p. 17-21.

Research output: Contribution to journalArticle

Angeli, SI, Poletti, BJ, Brackmann, DE, Carberry, JN, Xenellis, JE & Hitselberger, WE 1998, 'Primary lymphoma of the internal auditory canal. Case report and review of the literature', Annals of Otology, Rhinology and Laryngology, vol. 107, no. 1, pp. 17-21.
Angeli SI, Poletti BJ, Brackmann DE, Carberry JN, Xenellis JE, Hitselberger WE. Primary lymphoma of the internal auditory canal. Case report and review of the literature. Annals of Otology, Rhinology and Laryngology. 1998 Jan 29;107(1):17-21.
Angeli, Simon I ; Poletti, Bernard J. ; Brackmann, Derald E. ; Carberry, Joseph N. ; Xenellis, John E. ; Hitselberger, William E. / Primary lymphoma of the internal auditory canal. Case report and review of the literature. In: Annals of Otology, Rhinology and Laryngology. 1998 ; Vol. 107, No. 1. pp. 17-21.
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