A 14-year-old girl known to have trisomy 21 and who came to us with weight loss followed by hypertension proved to have diffuse arterial dysplasia involving the intimal layer (primary intimal fibroplasia). This is a rare cause of elevated blood pressure in children and has not been previously reported in a child with Down's syndrome. Unusual features of this case also include the widespread distribution of the lesions limited to the large muscular distributing arteries, the rapidly progressive course, and the predominance of abdominal signs and symptoms.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Diseases of Children|
|State||Published - Jul 1978|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health