Primary Intimal Fibroplasia in a Child With Down's Syndrome

Gary R. Fleisher, Billy E. Buck, David Cornfeld

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18 Scopus citations

Abstract

A 14-year-old girl known to have trisomy 21 and who came to us with weight loss followed by hypertension proved to have diffuse arterial dysplasia involving the intimal layer (primary intimal fibroplasia). This is a rare cause of elevated blood pressure in children and has not been previously reported in a child with Down's syndrome. Unusual features of this case also include the widespread distribution of the lesions limited to the large muscular distributing arteries, the rapidly progressive course, and the predominance of abdominal signs and symptoms.

Original languageEnglish (US)
Pages (from-to)700-703
Number of pages4
JournalAmerican Journal of Diseases of Children
Volume132
Issue number7
DOIs
StatePublished - Jul 1978

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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