Primary infantile glaucoma (congenital glaucoma)

Vincent P. deLuise, Douglas Anderson

Research output: Contribution to journalArticle

216 Citations (Scopus)

Abstract

Primary infantile glaucoma, commonly termed congenital glaucoma or trabeculodysgenesis, is an unusual, inherited connatal anomaly of the trabecular meshwork and anterior chamber angle which leads to obstruction of aqueous outflow, increased intraocular pressure, and optic nerve damage. Its pathogenesis is still disputed; most observers have not been able to document ultrastructurally a continuous endothelial membrane, as initially advanced by Barkan. Medical therapy for primary infantile glaucoma is accorded a supportive role; the primary, definitive treatment is surgical. Both goniotomy and trabeculotomy ab externo give similarly good results in the majority of patients. The prognosis in this disease is related to the time of its initial presentation, initial surgical intervention, degree of optic nerve damage, nature and quality of corneal enlargement and astigmatism, progressive refractive error, and anisometropic amblyopia. The inability to easily quantitate visual acuity and extent of visual loss in neonates makes these parameters less helpful in following patients than measurement of corneal diameter and intraocular pressure. However, even these data should not be relied upon exclusively to determine the quality or quantity of success in primary infantile glaucoma.

Original languageEnglish
Pages (from-to)1-19
Number of pages19
JournalSurvey of Ophthalmology
Volume28
Issue number1
DOIs
StatePublished - Jan 1 1983

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Glaucoma
Trabeculectomy
Optic Nerve
Intraocular Pressure
Trabecular Meshwork
Amblyopia
Refractive Errors
Astigmatism
Anterior Chamber
Visual Acuity
Newborn Infant
Membranes
Therapeutics

Keywords

  • buphthalmos
  • congenital glaucoma
  • goniotomy
  • hydrophthalmia
  • infantile glaucoma
  • primary infantile glaucoma
  • trabeculodysgenesis
  • trabeculotomy ab externo

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Primary infantile glaucoma (congenital glaucoma). / deLuise, Vincent P.; Anderson, Douglas.

In: Survey of Ophthalmology, Vol. 28, No. 1, 01.01.1983, p. 1-19.

Research output: Contribution to journalArticle

deLuise, Vincent P. ; Anderson, Douglas. / Primary infantile glaucoma (congenital glaucoma). In: Survey of Ophthalmology. 1983 ; Vol. 28, No. 1. pp. 1-19.
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