Primary immune deficiencies presenting in adults: Seven years of experience from Iran

Davood Mansouri, Parisa Adimi, Mehdi Mirsaedi, Nahal Mansouri, Payam Tabarsi, Majid Amiri, Hamid R. Jamaati, Masoud Motavasseli, Noushin Baghaii, Ali Cheraghvandi, Reza Rouhi, Navid A. Roozbahany, Soheila Zahirifard, Forouzan Mohammadi, Mohammad R. Masjedi, Ali A. Velayati, Jean L. Casanova, David P. Speert, R. Kevin Elwood, Robert SchellenbergStuart E. Turvey

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Primary immunodeficiencies (PIDs) are not solely diseases of childhood. We describe the clinical presentation and outcome for 55 adult patients with previously unrecognized PIDs. This series provides unique data regarding PIDs presenting in adulthood, and serves as a timely reminder that physicians must consider the diagnosis of PIDs in their adult patients. Using the experience gained from these patients, we outline key "warning signs" suggestive of an underlying PID. Only through increased physician awareness will patients with PIDs receive timely diagnosis and optimal management.

Original languageEnglish (US)
Pages (from-to)385-391
Number of pages7
JournalJournal of Clinical Immunology
Issue number4
StatePublished - Jul 2005
Externally publishedYes


  • Adults
  • Diagnostic delay
  • Iran
  • Primary immunodeficiency

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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