Primary cutaneous diffuse large B-cell lymphoma presenting as chronic non-healing ulcer

Victoria L. Billero; Charlotte E. Lasenna; Marco Romanelli; Alessio Giubellino; Robert A. Brenes; Paolo Romanelli

doi:10.1111/iwj.12716

Primary cutaneous diffuse large B-cell lymphoma presenting as chronic non-healing ulcer

Victoria L. Billero, Charlotte E. Lasenna, Marco Romanelli, Alessio Giubellino, Robert A. Brenes, Paolo Romanelli

Dermatology & Cutaneous Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Primary cutaneous diffuse large B-cell lymphoma is an uncommon and aggressive lymphoproliferative disorder with a rapid growth rate and dismal prognosis. We present the case of a 91-year-old female with an unusual manifestation of primary cutaneous diffuse large B-cell lymphoma, mimicking other more prevalent diseases like chronic non-healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non-healing leg ulcers.

Original language	English (US)
Journal	International Wound Journal
DOIs	https://doi.org/10.1111/iwj.12716
State	Accepted/In press - 2016

Keywords

Chronic ulcer
Dermatopathology
Leg ulcer
Non-healing ulcer
Primary cutaneous diffuse large B-cell lymphoma leg-type

ASJC Scopus subject areas

Surgery
Dermatology

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10.1111/iwj.12716

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Cite this

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title = "Primary cutaneous diffuse large B-cell lymphoma presenting as chronic non-healing ulcer",

abstract = "Primary cutaneous diffuse large B-cell lymphoma is an uncommon and aggressive lymphoproliferative disorder with a rapid growth rate and dismal prognosis. We present the case of a 91-year-old female with an unusual manifestation of primary cutaneous diffuse large B-cell lymphoma, mimicking other more prevalent diseases like chronic non-healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non-healing leg ulcers.",

keywords = "Chronic ulcer, Dermatopathology, Leg ulcer, Non-healing ulcer, Primary cutaneous diffuse large B-cell lymphoma leg-type",

author = "Billero, {Victoria L.} and Lasenna, {Charlotte E.} and Marco Romanelli and Alessio Giubellino and Brenes, {Robert A.} and Paolo Romanelli",

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AU - Billero, Victoria L.

AU - Lasenna, Charlotte E.

AU - Romanelli, Marco

AU - Giubellino, Alessio

AU - Brenes, Robert A.

AU - Romanelli, Paolo

PY - 2016

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AB - Primary cutaneous diffuse large B-cell lymphoma is an uncommon and aggressive lymphoproliferative disorder with a rapid growth rate and dismal prognosis. We present the case of a 91-year-old female with an unusual manifestation of primary cutaneous diffuse large B-cell lymphoma, mimicking other more prevalent diseases like chronic non-healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non-healing leg ulcers.

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KW - Dermatopathology

KW - Leg ulcer

KW - Non-healing ulcer

KW - Primary cutaneous diffuse large B-cell lymphoma leg-type

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