Primary carcinoid tumor of the cavernous sinus

Brian Hood, Eric Bray, Amade Bregy, Michael D Norenberg, Donald Weed, Jacques Morcos

Research output: Contribution to journalArticle

8 Scopus citations


Background Intracranial carcinoid tumors belong to the class of neuroendocrine tumors and their incidence is extremely rare. The pathogenesis and clinical manifestations of carcinoid tumors of the skull base are outlined in this case report. Case Description A 61-year-old multimorbid woman presented with transient memory loss. Computed tomographic and magnetic resonance imaging scan of the brain demonstrated a left cavernous sinus mass extending into the infratemporal fossa. The lesion was biopsied using the Caldwell-Luc approach, and histology showed a low-grade neuroendocrine tumor. The tumor was subtotally resected with a neurosurgery/head and neck combined preauricular infratemporal and subtemporal extradural approaches to the cavernous sinus. Further histologic evaluation revealed that the tumor was of carcinoid differentiation with no other primary or metastatic sites detectable. Conclusion Primary intracranial carcinoid tumors, though rare, should be included in the differential diagnosis of extradural and dural-based lesions.

Original languageEnglish (US)
Article number1948
Pages (from-to)202.E9-202.E13
JournalWorld Neurosurgery
Issue number1
StatePublished - 2014



  • Brain tumor
  • Cavernous sinus
  • Intracranial carcinoid
  • Neuroendocrine tumor

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

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