Prevention of stroke: Carotid artery disease and intracranial haemodynamic impairment as a risk factors for stroke

T. Rundek, V. Demarin, B. Mlacak, D. Runjic, S. Podobnik-Sarkanji, I. Mikula, A. Lovrencic-Huzjan

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background and purpose: A growing incidence of stroke has been observed in Croatia during last 3 years. This study presents the analysis of cerebral haemodynamic and other risk factors in stroke patients. Patients and methods: The analysis was performed in the group of 240 patients (53% male, mean age 57±13.78 years). In all patients we performed the brain CT Transcranial Doppler (TCD) and Color Doppler Flow Imaging of carotid artery (CDFI) within 3 days of the stroke onset. We evaluated other risk factors such as age, gender hypertension, peripheral vascular disease, serum cholesterol, ischaemic heart disease, diabetes mellitus and congestive heart failure. Results: The results showed the growing incidence of stroke in younger patients (40-60 years). The most frequent risk factors were: war stress, hypertension, diabetes, hyperlipidaemia, smoking, heart disease and carotid artery disease. The correlation analysis showed that the majority of patients with ischaemic stroke had the stenosis of internal carotid artery (ICA) more than 75%. A half of patients had decreased blood flow velocities (BFV) in the Willis' circle. Conclusions: Doppler ultrasound techniques are powerful tool for the early detection of carotid artery disease and cerebral haemodynamic disturbances, and therefore indispensable for stroke evaluation, prognosis and prevention. The impairment of cerebral haemodynamics is considered as the independent stroke risk factor.

Original languageEnglish (US)
Pages (from-to)133-137
Number of pages5
JournalPeriodicum Biologorum
Issue number2
StatePublished - Jan 1 1995
Externally publishedYes


  • Color Doppler of carotid artery
  • Risk factors
  • Stroke
  • Transcranial Doppler

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)


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