Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties.

R. Bullock; Y. Kuroda; G. M. Teasdale; J. McCulloch

doi:10.1007/978-3-7091-9233-7_15

Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties.

R. Bullock, Y. Kuroda, G. M. Teasdale, J. McCulloch

Neurological Surgery

Research output: Contribution to journal › Review article

34 Scopus citations

Abstract

Excitotoxic mechanisms due to overactivity of the amino acid neurotransmitters glutamate and aspartate maybe responsible for brain damage after injury. In this review we examine ischaemia and shear injury, which are relevant to human head injury. The opportunities for treatment using glutamate antagonist drugs are discussed.

Original language	English (US)
Pages (from-to)	49-55
Number of pages	7
Journal	Acta neurochirurgica. Supplementum
Volume	55
DOIs	https://doi.org/10.1007/978-3-7091-9233-7_15
State	Published - 1992

ASJC Scopus subject areas

Surgery
Clinical Neurology

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Bullock, R., Kuroda, Y., Teasdale, G. M., & McCulloch, J. (1992). Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties. Acta neurochirurgica. Supplementum, 55, 49-55. https://doi.org/10.1007/978-3-7091-9233-7_15

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