TY - JOUR
T1 - Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs
T2 - a new strategy for the nineties.
AU - Bullock, R.
AU - Kuroda, Y.
AU - Teasdale, G. M.
AU - McCulloch, J.
PY - 1992
Y1 - 1992
N2 - Excitotoxic mechanisms due to overactivity of the amino acid neurotransmitters glutamate and aspartate maybe responsible for brain damage after injury. In this review we examine ischaemia and shear injury, which are relevant to human head injury. The opportunities for treatment using glutamate antagonist drugs are discussed.
AB - Excitotoxic mechanisms due to overactivity of the amino acid neurotransmitters glutamate and aspartate maybe responsible for brain damage after injury. In this review we examine ischaemia and shear injury, which are relevant to human head injury. The opportunities for treatment using glutamate antagonist drugs are discussed.
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U2 - 10.1007/978-3-7091-9233-7_15
DO - 10.1007/978-3-7091-9233-7_15
M3 - Review article
C2 - 1357922
AN - SCOPUS:0026619299
VL - 55
SP - 49
EP - 55
JO - Acta Neurochirurgica, Supplement
JF - Acta Neurochirurgica, Supplement
SN - 0065-1419
ER -