Prevention of endomyometritis by local application of antibiotic solution during cesarean section

Lars P. Jensen, Ava J. Dobin, Mary Jo O'Sullivan, Charles E. Hilsenbeck

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Previous studies have demonstrated a reduction in the incidence of endomyometritis by using irrigation with 1000 ml of saline as a diluent at cesarean section. In this study 2 gm of cefoxitin sodium in 20 ml of saline solution was used for local application to the uterus and abdominal wound in 100 patients undergoing emergency cesarean section; results were compared to those in 100 patients who received no antibiotic at operation. Six patients in the treatment group developed endomyometritis as opposed to 33 in the untreated group (p < 0.001) and hospital stay was reduced by almost 2 days (p < 0.001). Local use of cefoxitin sodium appears effective in reducing the incidence of endomyometritis. A prospective double-blind study, however, is imperative before definite conclusions can be made.

Original languageEnglish (US)
Pages (from-to)565-568
Number of pages4
JournalAmerican journal of obstetrics and gynecology
Volume152
Issue number5
DOIs
StatePublished - Jul 1 1985

Keywords

  • antibiotics
  • cesarean section
  • Endomyometritis

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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