Preventing HIV infection: Pre-exposure and postexposure prophylaxis

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Data supporting the use of pre-exposure prophylaxis (PrEP) and nonoccupational postexposure prophylaxis (nPEP) in the prevention of HIV infection after a sexual encounter continue to grow. In this review, we describe some of the research driving the various recommendations for use of antiretrovirals in prevention. In addition, current research is described regarding the establishment of viral reservoirs that argues for rethinking the timing for nPEP treatment. We discuss the variables that impact on the choice of prevention antiretrovirals, including drug distribution, drug transporters, and potential impact of race and ethnicity on these variables.

Original languageEnglish (US)
Pages (from-to)453-461
Number of pages9
JournalIUBMB life
Issue number7
StatePublished - Jul 2014


  • antiretroviral medication
  • human immunodeficiency virus
  • prevention

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Clinical Biochemistry
  • Molecular Biology
  • Genetics


Dive into the research topics of 'Preventing HIV infection: Pre-exposure and postexposure prophylaxis'. Together they form a unique fingerprint.

Cite this