Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study

Josefina Medina-Lezama, Humberto Zea-Diaz, Oscar L. Morey-Vargas, Juan F. Bolaños-Salazar, Edgar Muñoz-Atahualpa, Mauricio Postigo-MacDowall, Fernando Corrales-Medina, Zoila Valdivia-Ascuña, Carolina Cuba-Bustinza, Sheyla Paredes-Díaz, Paola Villalobos-Tapia, Julio Chirinos-Pacheco, Ronald B Goldberg, Julio A. Chirinos

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Data regarding the prevalence of metabolic syndrome (MTS) in Andean populations are limited. We evaluated the prevalence of MTS according to American Heart Association/National Heart, Lung and Blood Institute criteria among 1878 subjects in the PREVENCION study in Peru. In women, the most common component was low HDL cholesterol (60.9%) followed by abdominal obesity (36.9%). In men, the most common component was elevated triglycerides (52.0%) followed by low HDL cholesterol (32.5%), whereas the prevalence of abdominal obesity was 14%. Abnormal fasting glucose was the least common component in men (5.4%) and women (5.0%). The prevalence of MTS was significantly higher in women compared to men (23.2% versus 14.3%) and increased steeply with age, particularly in women (p < 0.0001). Using body mass index (BMI ≥ 30 kg/m2) instead of waist circumference as a component of the MTS lead to equivalent prevalence estimates of MTS in men but significantly underestimated the prevalence in women. The MTS is highly prevalent among Peruvian Andeans, particularly in older women. The pattern of MTS components in this Andean population is characterized by a high prevalence of dyslipidemia and a relatively low prevalence of elevated fasting glucose. Further studies are required to characterize genetic and environmental determinants of these patterns.

Original languageEnglish
Pages (from-to)270-281
Number of pages12
JournalDiabetes Research and Clinical Practice
Volume78
Issue number2
DOIs
StatePublished - Nov 1 2007

Fingerprint

Hispanic Americans
Abdominal Obesity
HDL Cholesterol
Fasting
National Heart, Lung, and Blood Institute (U.S.)
Glucose
Peru
Waist Circumference
Dyslipidemias
Population
Triglycerides
Body Mass Index

Keywords

  • Andeans
  • Latin America
  • Metabolic syndrome
  • Prevalence
  • Risk factors
  • Special populations

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Medina-Lezama, J., Zea-Diaz, H., Morey-Vargas, O. L., Bolaños-Salazar, J. F., Muñoz-Atahualpa, E., Postigo-MacDowall, M., ... Chirinos, J. A. (2007). Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study. Diabetes Research and Clinical Practice, 78(2), 270-281. https://doi.org/10.1016/j.diabres.2007.04.004

Prevalence of the metabolic syndrome in Peruvian Andean hispanics : The PREVENCION study. / Medina-Lezama, Josefina; Zea-Diaz, Humberto; Morey-Vargas, Oscar L.; Bolaños-Salazar, Juan F.; Muñoz-Atahualpa, Edgar; Postigo-MacDowall, Mauricio; Corrales-Medina, Fernando; Valdivia-Ascuña, Zoila; Cuba-Bustinza, Carolina; Paredes-Díaz, Sheyla; Villalobos-Tapia, Paola; Chirinos-Pacheco, Julio; Goldberg, Ronald B; Chirinos, Julio A.

In: Diabetes Research and Clinical Practice, Vol. 78, No. 2, 01.11.2007, p. 270-281.

Research output: Contribution to journalArticle

Medina-Lezama, J, Zea-Diaz, H, Morey-Vargas, OL, Bolaños-Salazar, JF, Muñoz-Atahualpa, E, Postigo-MacDowall, M, Corrales-Medina, F, Valdivia-Ascuña, Z, Cuba-Bustinza, C, Paredes-Díaz, S, Villalobos-Tapia, P, Chirinos-Pacheco, J, Goldberg, RB & Chirinos, JA 2007, 'Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study', Diabetes Research and Clinical Practice, vol. 78, no. 2, pp. 270-281. https://doi.org/10.1016/j.diabres.2007.04.004
Medina-Lezama J, Zea-Diaz H, Morey-Vargas OL, Bolaños-Salazar JF, Muñoz-Atahualpa E, Postigo-MacDowall M et al. Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study. Diabetes Research and Clinical Practice. 2007 Nov 1;78(2):270-281. https://doi.org/10.1016/j.diabres.2007.04.004
Medina-Lezama, Josefina ; Zea-Diaz, Humberto ; Morey-Vargas, Oscar L. ; Bolaños-Salazar, Juan F. ; Muñoz-Atahualpa, Edgar ; Postigo-MacDowall, Mauricio ; Corrales-Medina, Fernando ; Valdivia-Ascuña, Zoila ; Cuba-Bustinza, Carolina ; Paredes-Díaz, Sheyla ; Villalobos-Tapia, Paola ; Chirinos-Pacheco, Julio ; Goldberg, Ronald B ; Chirinos, Julio A. / Prevalence of the metabolic syndrome in Peruvian Andean hispanics : The PREVENCION study. In: Diabetes Research and Clinical Practice. 2007 ; Vol. 78, No. 2. pp. 270-281.
@article{b3043bb779394bdba0a92909c882503e,
title = "Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study",
abstract = "Data regarding the prevalence of metabolic syndrome (MTS) in Andean populations are limited. We evaluated the prevalence of MTS according to American Heart Association/National Heart, Lung and Blood Institute criteria among 1878 subjects in the PREVENCION study in Peru. In women, the most common component was low HDL cholesterol (60.9{\%}) followed by abdominal obesity (36.9{\%}). In men, the most common component was elevated triglycerides (52.0{\%}) followed by low HDL cholesterol (32.5{\%}), whereas the prevalence of abdominal obesity was 14{\%}. Abnormal fasting glucose was the least common component in men (5.4{\%}) and women (5.0{\%}). The prevalence of MTS was significantly higher in women compared to men (23.2{\%} versus 14.3{\%}) and increased steeply with age, particularly in women (p < 0.0001). Using body mass index (BMI ≥ 30 kg/m2) instead of waist circumference as a component of the MTS lead to equivalent prevalence estimates of MTS in men but significantly underestimated the prevalence in women. The MTS is highly prevalent among Peruvian Andeans, particularly in older women. The pattern of MTS components in this Andean population is characterized by a high prevalence of dyslipidemia and a relatively low prevalence of elevated fasting glucose. Further studies are required to characterize genetic and environmental determinants of these patterns.",
keywords = "Andeans, Latin America, Metabolic syndrome, Prevalence, Risk factors, Special populations",
author = "Josefina Medina-Lezama and Humberto Zea-Diaz and Morey-Vargas, {Oscar L.} and Bola{\~n}os-Salazar, {Juan F.} and Edgar Mu{\~n}oz-Atahualpa and Mauricio Postigo-MacDowall and Fernando Corrales-Medina and Zoila Valdivia-Ascu{\~n}a and Carolina Cuba-Bustinza and Sheyla Paredes-D{\'i}az and Paola Villalobos-Tapia and Julio Chirinos-Pacheco and Goldberg, {Ronald B} and Chirinos, {Julio A.}",
year = "2007",
month = "11",
day = "1",
doi = "10.1016/j.diabres.2007.04.004",
language = "English",
volume = "78",
pages = "270--281",
journal = "Diabetes Research and Clinical Practice",
issn = "0168-8227",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Prevalence of the metabolic syndrome in Peruvian Andean hispanics

T2 - The PREVENCION study

AU - Medina-Lezama, Josefina

AU - Zea-Diaz, Humberto

AU - Morey-Vargas, Oscar L.

AU - Bolaños-Salazar, Juan F.

AU - Muñoz-Atahualpa, Edgar

AU - Postigo-MacDowall, Mauricio

AU - Corrales-Medina, Fernando

AU - Valdivia-Ascuña, Zoila

AU - Cuba-Bustinza, Carolina

AU - Paredes-Díaz, Sheyla

AU - Villalobos-Tapia, Paola

AU - Chirinos-Pacheco, Julio

AU - Goldberg, Ronald B

AU - Chirinos, Julio A.

PY - 2007/11/1

Y1 - 2007/11/1

N2 - Data regarding the prevalence of metabolic syndrome (MTS) in Andean populations are limited. We evaluated the prevalence of MTS according to American Heart Association/National Heart, Lung and Blood Institute criteria among 1878 subjects in the PREVENCION study in Peru. In women, the most common component was low HDL cholesterol (60.9%) followed by abdominal obesity (36.9%). In men, the most common component was elevated triglycerides (52.0%) followed by low HDL cholesterol (32.5%), whereas the prevalence of abdominal obesity was 14%. Abnormal fasting glucose was the least common component in men (5.4%) and women (5.0%). The prevalence of MTS was significantly higher in women compared to men (23.2% versus 14.3%) and increased steeply with age, particularly in women (p < 0.0001). Using body mass index (BMI ≥ 30 kg/m2) instead of waist circumference as a component of the MTS lead to equivalent prevalence estimates of MTS in men but significantly underestimated the prevalence in women. The MTS is highly prevalent among Peruvian Andeans, particularly in older women. The pattern of MTS components in this Andean population is characterized by a high prevalence of dyslipidemia and a relatively low prevalence of elevated fasting glucose. Further studies are required to characterize genetic and environmental determinants of these patterns.

AB - Data regarding the prevalence of metabolic syndrome (MTS) in Andean populations are limited. We evaluated the prevalence of MTS according to American Heart Association/National Heart, Lung and Blood Institute criteria among 1878 subjects in the PREVENCION study in Peru. In women, the most common component was low HDL cholesterol (60.9%) followed by abdominal obesity (36.9%). In men, the most common component was elevated triglycerides (52.0%) followed by low HDL cholesterol (32.5%), whereas the prevalence of abdominal obesity was 14%. Abnormal fasting glucose was the least common component in men (5.4%) and women (5.0%). The prevalence of MTS was significantly higher in women compared to men (23.2% versus 14.3%) and increased steeply with age, particularly in women (p < 0.0001). Using body mass index (BMI ≥ 30 kg/m2) instead of waist circumference as a component of the MTS lead to equivalent prevalence estimates of MTS in men but significantly underestimated the prevalence in women. The MTS is highly prevalent among Peruvian Andeans, particularly in older women. The pattern of MTS components in this Andean population is characterized by a high prevalence of dyslipidemia and a relatively low prevalence of elevated fasting glucose. Further studies are required to characterize genetic and environmental determinants of these patterns.

KW - Andeans

KW - Latin America

KW - Metabolic syndrome

KW - Prevalence

KW - Risk factors

KW - Special populations

UR - http://www.scopus.com/inward/record.url?scp=34548840520&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548840520&partnerID=8YFLogxK

U2 - 10.1016/j.diabres.2007.04.004

DO - 10.1016/j.diabres.2007.04.004

M3 - Article

C2 - 17524517

AN - SCOPUS:34548840520

VL - 78

SP - 270

EP - 281

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

SN - 0168-8227

IS - 2

ER -