Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study

Josefina Medina-Lezama, Humberto Zea-Diaz, Oscar L. Morey-Vargas, Juan F. Bolaños-Salazar, Edgar Muñoz-Atahualpa, Mauricio Postigo-MacDowall, Fernando Corrales-Medina, Zoila Valdivia-Ascuña, Carolina Cuba-Bustinza, Sheyla Paredes-Díaz, Paola Villalobos-Tapia, Julio Chirinos-Pacheco, Ronald B. Goldberg, Julio A. Chirinos

Research output: Contribution to journalArticle

53 Scopus citations

Abstract

Data regarding the prevalence of metabolic syndrome (MTS) in Andean populations are limited. We evaluated the prevalence of MTS according to American Heart Association/National Heart, Lung and Blood Institute criteria among 1878 subjects in the PREVENCION study in Peru. In women, the most common component was low HDL cholesterol (60.9%) followed by abdominal obesity (36.9%). In men, the most common component was elevated triglycerides (52.0%) followed by low HDL cholesterol (32.5%), whereas the prevalence of abdominal obesity was 14%. Abnormal fasting glucose was the least common component in men (5.4%) and women (5.0%). The prevalence of MTS was significantly higher in women compared to men (23.2% versus 14.3%) and increased steeply with age, particularly in women (p < 0.0001). Using body mass index (BMI ≥ 30 kg/m2) instead of waist circumference as a component of the MTS lead to equivalent prevalence estimates of MTS in men but significantly underestimated the prevalence in women. The MTS is highly prevalent among Peruvian Andeans, particularly in older women. The pattern of MTS components in this Andean population is characterized by a high prevalence of dyslipidemia and a relatively low prevalence of elevated fasting glucose. Further studies are required to characterize genetic and environmental determinants of these patterns.

Original languageEnglish (US)
Pages (from-to)270-281
Number of pages12
JournalDiabetes research and clinical practice
Volume78
Issue number2
DOIs
StatePublished - Nov 1 2007

Keywords

  • Andeans
  • Latin America
  • Metabolic syndrome
  • Prevalence
  • Risk factors
  • Special populations

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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    Medina-Lezama, J., Zea-Diaz, H., Morey-Vargas, O. L., Bolaños-Salazar, J. F., Muñoz-Atahualpa, E., Postigo-MacDowall, M., Corrales-Medina, F., Valdivia-Ascuña, Z., Cuba-Bustinza, C., Paredes-Díaz, S., Villalobos-Tapia, P., Chirinos-Pacheco, J., Goldberg, R. B., & Chirinos, J. A. (2007). Prevalence of the metabolic syndrome in Peruvian Andean hispanics: The PREVENCION study. Diabetes research and clinical practice, 78(2), 270-281. https://doi.org/10.1016/j.diabres.2007.04.004