Prevalence of low bone mineral density in a low-income inner-city population

Diala El-Maouche, Xiaoqiang Xu, Joseph Cofrancesco, Adrian S. Dobs, Todd T. Brown

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Bone mineral density (BMD) is an important factor linked to bone health. Little is known of the prevalence of low BMD and its associated risk factors in an urban underserved population. Between 2001 and 2004, we recruited 338 subjects who completed drug use and medical history questionnaires, underwent hormonal measurements, and underwent whole-body dual-energy X-ray absorptiometry (DXA) for evaluation of BMD and body composition. Of these, 132 subjects had site-specific DXA (lumbar spine and hip) performed. Osteoporosis was defined as a T-score of -2.5 or less for men 50 years of age and older and postmenopausal women and a Z-score of -2.0 or less in men younger than 50 years of age and premenopausal women at either the lumbar spine, total hip, or femoral neck, according to National Osteoporosis Foundation (NOF) guidelines. The cohort consisted of mostly African-American, middle-aged people with a high prevalence of illicit drug use, 50% HIV+, and 39% hepatitis C+. Osteoporosis was identified in 22% of subjects (24 men, 5 women), with the majority of cases (90%) attributable to osteoporosis at the lumbar spine. Osteoporosis was more common in men than in women. Lower whole-body BMD among women was associated with multiple risk factors, but only with lower lean mass among men. Osteoporosis was highly prevalent in men, mainly at the spine. The risk factors for bone loss in this population need to be further clarified. Screening men for osteoporosis starting at age 50 might be warranted in this population given the multiple risk factors and the unexpectedly high prevalence of low BMD.

Original languageEnglish (US)
Pages (from-to)388-396
Number of pages9
JournalJournal of Bone and Mineral Research
Volume26
Issue number2
DOIs
StatePublished - Feb 2011
Externally publishedYes

Fingerprint

Bone Density
Osteoporosis
Spine
Population
Photon Absorptiometry
Hip
Bone and Bones
Urban Population
Femur Neck
Street Drugs
Vulnerable Populations
Hepatitis C
Body Composition
African Americans
HIV
Guidelines
Health
Pharmaceutical Preparations

Keywords

  • BMI
  • BONE MINERAL DENSITY
  • HIV
  • INNER CITY
  • OSTEOPOROSIS

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

El-Maouche, D., Xu, X., Cofrancesco, J., Dobs, A. S., & Brown, T. T. (2011). Prevalence of low bone mineral density in a low-income inner-city population. Journal of Bone and Mineral Research, 26(2), 388-396. https://doi.org/10.1002/jbmr.221

Prevalence of low bone mineral density in a low-income inner-city population. / El-Maouche, Diala; Xu, Xiaoqiang; Cofrancesco, Joseph; Dobs, Adrian S.; Brown, Todd T.

In: Journal of Bone and Mineral Research, Vol. 26, No. 2, 02.2011, p. 388-396.

Research output: Contribution to journalArticle

El-Maouche, D, Xu, X, Cofrancesco, J, Dobs, AS & Brown, TT 2011, 'Prevalence of low bone mineral density in a low-income inner-city population', Journal of Bone and Mineral Research, vol. 26, no. 2, pp. 388-396. https://doi.org/10.1002/jbmr.221
El-Maouche, Diala ; Xu, Xiaoqiang ; Cofrancesco, Joseph ; Dobs, Adrian S. ; Brown, Todd T. / Prevalence of low bone mineral density in a low-income inner-city population. In: Journal of Bone and Mineral Research. 2011 ; Vol. 26, No. 2. pp. 388-396.
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