Prevalence of intracranial emboli signals in patients with carotid and cardiac disease

T. Rundek, V. Demarin, K. Niederkorn, V. Vukovic, S. Podobnik-Sarkanji, D. Runjic, A. Lovrencic-Huzjan, B. Starcevic, D. Richter, D. Planinc

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


A total of 70 stroke patients were analyzed by Transcranial Doppler (TCD) to detect the prevalence of cerebral emboli. Thirty-five patients had extracranial carotid artery disease (11 with stenosis >80% and 24 with stenosis <79%) and 35 patients had atrial fibrillation (AF). Simultaneous TCD monitoring of both middle cerebral arteries (MCA) over 30 minutes was carried out by Multi-Dop X (DWL). The number of emboli signals was categorized according to the intensity of the Doppler amplitude into 6 groups: 3, 6, 9, 12, 15, and >18 dB. All patients had detectable signals of 3 and 6 dB amplitudes, and 32 patients (91%) had emboli signals higher than 12 dB. In the patients with AF the average distribution of emboli signals was: 7, 21, 43, 12, 3, 0/30 min, in those with carotid stenosis >80%: 3, 21, 19, 13, 11, 4/30 min, and in the patients with stenosis <79%: 1, 2, 3, 2, 2, 1/30 min (p<0.01). No statistically significant difference in the emboli prevalence between the left and right MCA was found. The patients with AF and those with carotid stenosis >80% had a higher prevalence of emboli signals of >12 dB amplitude (56 signals/30 min, 49 signals/30 min) than the patients with carotid stenosis <79% (24 signals/30 min), p<0.01. Doppler monitoring of cerebral emboli is a new method for the detection of subclinical embolization with a potential value for the stroke therapy, prognosis and prevention.

Original languageEnglish (US)
Pages (from-to)137-143
Number of pages7
JournalActa Clinica Croatica
Issue number3
StatePublished - Dec 1 1995
Externally publishedYes


  • Atrial fibrillation
  • Carotid artery stenosis
  • Cerebral emboli
  • Transcranial Doppler

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Prevalence of intracranial emboli signals in patients with carotid and cardiac disease'. Together they form a unique fingerprint.

Cite this