Prevalence of intracranial emboli signals in patients with carotid and cardiac disease

Tatjana Rundek, V. Demarin, K. Niederkorn, V. Vukovic, S. Podobnik-Sarkanji, D. Runjic, A. Lovrencic-Huzjan, B. Starcevic, D. Richter, D. Planinc

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A total of 70 stroke patients were analyzed by Transcranial Doppler (TCD) to detect the prevalence of cerebral emboli. Thirty-five patients had extracranial carotid artery disease (11 with stenosis >80% and 24 with stenosis <79%) and 35 patients had atrial fibrillation (AF). Simultaneous TCD monitoring of both middle cerebral arteries (MCA) over 30 minutes was carried out by Multi-Dop X (DWL). The number of emboli signals was categorized according to the intensity of the Doppler amplitude into 6 groups: 3, 6, 9, 12, 15, and >18 dB. All patients had detectable signals of 3 and 6 dB amplitudes, and 32 patients (91%) had emboli signals higher than 12 dB. In the patients with AF the average distribution of emboli signals was: 7, 21, 43, 12, 3, 0/30 min, in those with carotid stenosis >80%: 3, 21, 19, 13, 11, 4/30 min, and in the patients with stenosis <79%: 1, 2, 3, 2, 2, 1/30 min (p<0.01). No statistically significant difference in the emboli prevalence between the left and right MCA was found. The patients with AF and those with carotid stenosis >80% had a higher prevalence of emboli signals of >12 dB amplitude (56 signals/30 min, 49 signals/30 min) than the patients with carotid stenosis <79% (24 signals/30 min), p<0.01. Doppler monitoring of cerebral emboli is a new method for the detection of subclinical embolization with a potential value for the stroke therapy, prognosis and prevention.

Original languageEnglish
Pages (from-to)137-143
Number of pages7
JournalActa Clinica Croatica
Volume34
Issue number3
StatePublished - Dec 1 1995
Externally publishedYes

Fingerprint

Embolism
Heart Diseases
Intracranial Embolism
Pathologic Constriction
Carotid Stenosis
Stroke
Carotid Artery Diseases

Keywords

  • Atrial fibrillation
  • Carotid artery stenosis
  • Cerebral emboli
  • Transcranial Doppler

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Rundek, T., Demarin, V., Niederkorn, K., Vukovic, V., Podobnik-Sarkanji, S., Runjic, D., ... Planinc, D. (1995). Prevalence of intracranial emboli signals in patients with carotid and cardiac disease. Acta Clinica Croatica, 34(3), 137-143.

Prevalence of intracranial emboli signals in patients with carotid and cardiac disease. / Rundek, Tatjana; Demarin, V.; Niederkorn, K.; Vukovic, V.; Podobnik-Sarkanji, S.; Runjic, D.; Lovrencic-Huzjan, A.; Starcevic, B.; Richter, D.; Planinc, D.

In: Acta Clinica Croatica, Vol. 34, No. 3, 01.12.1995, p. 137-143.

Research output: Contribution to journalArticle

Rundek, T, Demarin, V, Niederkorn, K, Vukovic, V, Podobnik-Sarkanji, S, Runjic, D, Lovrencic-Huzjan, A, Starcevic, B, Richter, D & Planinc, D 1995, 'Prevalence of intracranial emboli signals in patients with carotid and cardiac disease', Acta Clinica Croatica, vol. 34, no. 3, pp. 137-143.
Rundek T, Demarin V, Niederkorn K, Vukovic V, Podobnik-Sarkanji S, Runjic D et al. Prevalence of intracranial emboli signals in patients with carotid and cardiac disease. Acta Clinica Croatica. 1995 Dec 1;34(3):137-143.
Rundek, Tatjana ; Demarin, V. ; Niederkorn, K. ; Vukovic, V. ; Podobnik-Sarkanji, S. ; Runjic, D. ; Lovrencic-Huzjan, A. ; Starcevic, B. ; Richter, D. ; Planinc, D. / Prevalence of intracranial emboli signals in patients with carotid and cardiac disease. In: Acta Clinica Croatica. 1995 ; Vol. 34, No. 3. pp. 137-143.
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abstract = "A total of 70 stroke patients were analyzed by Transcranial Doppler (TCD) to detect the prevalence of cerebral emboli. Thirty-five patients had extracranial carotid artery disease (11 with stenosis >80{\%} and 24 with stenosis <79{\%}) and 35 patients had atrial fibrillation (AF). Simultaneous TCD monitoring of both middle cerebral arteries (MCA) over 30 minutes was carried out by Multi-Dop X (DWL). The number of emboli signals was categorized according to the intensity of the Doppler amplitude into 6 groups: 3, 6, 9, 12, 15, and >18 dB. All patients had detectable signals of 3 and 6 dB amplitudes, and 32 patients (91{\%}) had emboli signals higher than 12 dB. In the patients with AF the average distribution of emboli signals was: 7, 21, 43, 12, 3, 0/30 min, in those with carotid stenosis >80{\%}: 3, 21, 19, 13, 11, 4/30 min, and in the patients with stenosis <79{\%}: 1, 2, 3, 2, 2, 1/30 min (p<0.01). No statistically significant difference in the emboli prevalence between the left and right MCA was found. The patients with AF and those with carotid stenosis >80{\%} had a higher prevalence of emboli signals of >12 dB amplitude (56 signals/30 min, 49 signals/30 min) than the patients with carotid stenosis <79{\%} (24 signals/30 min), p<0.01. Doppler monitoring of cerebral emboli is a new method for the detection of subclinical embolization with a potential value for the stroke therapy, prognosis and prevention.",
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AU - Runjic, D.

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