TY - JOUR
T1 - Prevalence and patterns of hypertension in Peruvian Andean Hispanics
T2 - the PREVENCION study
AU - Medina-Lezama, Josefina
AU - Zea-Diaz, Humberto
AU - Morey-Vargas, Oscar L.
AU - Bolaños-Salazar, Juan F.
AU - Postigo-MacDowall, Mauricio
AU - Paredes-Díaz, Sheyla
AU - Corrales-Medina, Fernando
AU - Valdivia-Ascuña, Zoila
AU - Cuba-Bustinza, Carolina
AU - Villalobos-Tapia, Paola
AU - Muñoz-Atahualpa, Edgar
AU - Chirinos-Pacheco, Julio
AU - Raij, Leopoldo
AU - Chirinos, Julio A.
PY - 2007/5/1
Y1 - 2007/5/1
N2 - Cardiovascular disease is emerging as a leading cause of morbidity and mortality in Latin America. Population-based data regarding the prevalence of hypertension and hypertension subtypes in Andean Hispanic populations are scarce. The authors performed a population-based study that included 1878 Peruvian Andean adults to determine: (1) the prevalence, awareness, and control of hypertension and (2) the relative frequency of hypertension subtypes (systolic vs. diastolic). The prevalence of hypertension was 15.7% (95% confidence interval [CI], 14.0%-17.4%), did not differ by gender, and increased steeply with age, particularly in women. Awareness, treatment, and control rates were 47.9%, 39.5%, and 14%, respectively. Diastolic blood pressure increased until age 50 years and reached a plateau thereafter, whereas mean arterial pressure continued to increase with age even after age 50 years. Furthermore, in sharp contrast with the United States population, the predominant type of hypertension was systodiastolic (41.7%; 95% CI, 35.1%-48.5%). Isolated systolic hypertension accounted for only 29.3% of cases (95% CI, 23.9%-35.4%) and was responsible for a minority of cases in all age groups before age 70 years. Hypertension subtypes in this Andean population seem to differ significantly from those present in the United States population, with a much larger proportion of systodiastolic and diastolic hypertension even with advanced age. These differences result from interactions between hemodynamic and structural factors, and further studies aimed at characterizing their genetic and environmental determinants and implications in end-organ damage and prognosis in this population may contribute to understanding the pathophysiology of hypertension.
AB - Cardiovascular disease is emerging as a leading cause of morbidity and mortality in Latin America. Population-based data regarding the prevalence of hypertension and hypertension subtypes in Andean Hispanic populations are scarce. The authors performed a population-based study that included 1878 Peruvian Andean adults to determine: (1) the prevalence, awareness, and control of hypertension and (2) the relative frequency of hypertension subtypes (systolic vs. diastolic). The prevalence of hypertension was 15.7% (95% confidence interval [CI], 14.0%-17.4%), did not differ by gender, and increased steeply with age, particularly in women. Awareness, treatment, and control rates were 47.9%, 39.5%, and 14%, respectively. Diastolic blood pressure increased until age 50 years and reached a plateau thereafter, whereas mean arterial pressure continued to increase with age even after age 50 years. Furthermore, in sharp contrast with the United States population, the predominant type of hypertension was systodiastolic (41.7%; 95% CI, 35.1%-48.5%). Isolated systolic hypertension accounted for only 29.3% of cases (95% CI, 23.9%-35.4%) and was responsible for a minority of cases in all age groups before age 70 years. Hypertension subtypes in this Andean population seem to differ significantly from those present in the United States population, with a much larger proportion of systodiastolic and diastolic hypertension even with advanced age. These differences result from interactions between hemodynamic and structural factors, and further studies aimed at characterizing their genetic and environmental determinants and implications in end-organ damage and prognosis in this population may contribute to understanding the pathophysiology of hypertension.
KW - Hypertension
KW - Latin America
KW - Peru
KW - prevalence
KW - risk factors
KW - special populations
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UR - http://www.scopus.com/inward/citedby.url?scp=34249111960&partnerID=8YFLogxK
U2 - 10.1016/j.jash.2007.02.003
DO - 10.1016/j.jash.2007.02.003
M3 - Article
C2 - 20409853
AN - SCOPUS:34249111960
VL - 1
SP - 216
EP - 225
JO - Journal of the American Society of Hypertension
JF - Journal of the American Society of Hypertension
SN - 1933-1711
IS - 3
ER -