Prevalence and Clinical Correlates of Mitral Annulus Calcification in Hispanics and non-Hispanic Whites

Howard J. Willens, Julio A. Chirinos, Charles H. Hennekens

Research output: Contribution to journalArticle

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Abstract

Background: Data about mitral annulus calcification (MAC) are sparse in Hispanics. We compare prevalence and clinical correlates of MAC in Hispanics and non-Hispanic whites. Methods: We reviewed echocardiograms and clinical data of 337 Hispanics and 279 non-Hispanic whites, age 45 to 75 years. In cross-sectional data, prevalence and interrelationships of MAC, coronary heart disease (CHD), and risk factors were compared using multivariable logistic regression. Results: In Hispanics, MAC was significantly associated with CHD (odds ratio [OR] = 2.06, confidence interval [CI] = 1.09-3.87), age (OR = 1.73, CI = 1.21-2.49), female sex (OR = 1.87, CI = 1.01-3.47), smoking (OR = 1.80, CI = 1.01-3.24), and having multiple (>2) risk factors (OR = 3.43, CI = 2.66-4.43). In non-Hispanic whites, MAC was associated with CHD (OR = 4.24, CI = 2.00-8.98), age (OR = 2.87, CI = 1.82-4.50), and having multiple risk factors (OR = 3.59, CI = 2.7-4.77). There were no significant ethnic differences in prevalence of MAC. Conclusions: Among Hispanics referred for echocardiography, MAC is associated with CHD and risk factors.

Original languageEnglish
Pages (from-to)191-196
Number of pages6
JournalJournal of the American Society of Echocardiography
Volume20
Issue number2
DOIs
StatePublished - Feb 1 2007
Externally publishedYes

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Hispanic Americans
Odds Ratio
Confidence Intervals
Coronary Disease
Sex Ratio
Echocardiography
Logistic Models
Smoking

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Prevalence and Clinical Correlates of Mitral Annulus Calcification in Hispanics and non-Hispanic Whites. / Willens, Howard J.; Chirinos, Julio A.; Hennekens, Charles H.

In: Journal of the American Society of Echocardiography, Vol. 20, No. 2, 01.02.2007, p. 191-196.

Research output: Contribution to journalArticle

Willens, Howard J. ; Chirinos, Julio A. ; Hennekens, Charles H. / Prevalence and Clinical Correlates of Mitral Annulus Calcification in Hispanics and non-Hispanic Whites. In: Journal of the American Society of Echocardiography. 2007 ; Vol. 20, No. 2. pp. 191-196.
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abstract = "Background: Data about mitral annulus calcification (MAC) are sparse in Hispanics. We compare prevalence and clinical correlates of MAC in Hispanics and non-Hispanic whites. Methods: We reviewed echocardiograms and clinical data of 337 Hispanics and 279 non-Hispanic whites, age 45 to 75 years. In cross-sectional data, prevalence and interrelationships of MAC, coronary heart disease (CHD), and risk factors were compared using multivariable logistic regression. Results: In Hispanics, MAC was significantly associated with CHD (odds ratio [OR] = 2.06, confidence interval [CI] = 1.09-3.87), age (OR = 1.73, CI = 1.21-2.49), female sex (OR = 1.87, CI = 1.01-3.47), smoking (OR = 1.80, CI = 1.01-3.24), and having multiple (>2) risk factors (OR = 3.43, CI = 2.66-4.43). In non-Hispanic whites, MAC was associated with CHD (OR = 4.24, CI = 2.00-8.98), age (OR = 2.87, CI = 1.82-4.50), and having multiple risk factors (OR = 3.59, CI = 2.7-4.77). There were no significant ethnic differences in prevalence of MAC. Conclusions: Among Hispanics referred for echocardiography, MAC is associated with CHD and risk factors.",
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