Pretibial Myxedema Masquerading as a Venous Leg Ulcer

Ingrid Herskovitz, Olivia Hughes, Flor MacQuhae, Robert Kirsner

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The authors report a case of pretibial myxedema (PTM) masquerading as a venous leg ulcer to alert wound care clinicians to this diagnostic possibility. Pretibial myxedema is a localized form of mucin cutaneous deposition characterized by indurated plaques most commonly on anterior legs. It is more likely to present in patients with Graves' disease, but it can be found in euthyroid patients as well. The physiopathology of PTM is complex, and there is an accumulation of highly hydrophilic glycosaminoglycans in the dermis. Minimal morbidity is associated with PTM, but the pruritus related to mucin deposition can be intense. The skin around venous leg ulcers and the skin changes related to PTM can have a similar clinical presentation, which may be a reason PTM is under-recognized.

Original languageEnglish (US)
Pages (from-to)77-79
Number of pages3
JournalWounds
Volume29
Issue number3
StatePublished - Mar 1 2017

Fingerprint

Myxedema
Varicose Ulcer
Leg Ulcer
Mucins
Skin
Graves Disease
Pruritus
Dermis
Glycosaminoglycans
Leg
Morbidity
Wounds and Injuries

Keywords

  • lower extremity
  • Pretibial myxedema
  • venous leg ulcer

ASJC Scopus subject areas

  • Surgery
  • Medical–Surgical

Cite this

Herskovitz, I., Hughes, O., MacQuhae, F., & Kirsner, R. (2017). Pretibial Myxedema Masquerading as a Venous Leg Ulcer. Wounds, 29(3), 77-79.

Pretibial Myxedema Masquerading as a Venous Leg Ulcer. / Herskovitz, Ingrid; Hughes, Olivia; MacQuhae, Flor; Kirsner, Robert.

In: Wounds, Vol. 29, No. 3, 01.03.2017, p. 77-79.

Research output: Contribution to journalArticle

Herskovitz, I, Hughes, O, MacQuhae, F & Kirsner, R 2017, 'Pretibial Myxedema Masquerading as a Venous Leg Ulcer', Wounds, vol. 29, no. 3, pp. 77-79.
Herskovitz I, Hughes O, MacQuhae F, Kirsner R. Pretibial Myxedema Masquerading as a Venous Leg Ulcer. Wounds. 2017 Mar 1;29(3):77-79.
Herskovitz, Ingrid ; Hughes, Olivia ; MacQuhae, Flor ; Kirsner, Robert. / Pretibial Myxedema Masquerading as a Venous Leg Ulcer. In: Wounds. 2017 ; Vol. 29, No. 3. pp. 77-79.
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