Pressure effect on ERG and optic nerve conduction of visual impulse: short term effects in owl monkeys

C. L. Gerstle, Douglas Anderson, D. I. Hamasaki

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The effects of increased intraocular pressure on optic tract responses and the electroretinogram (ERG) b wave were studied in owl monkeys. Both responses showed a decrease in amplitude only if the intraocular pressures exceeded a certain critical level, which was about 30 mm Hg below mean femoral blood pressure. Above this intraocular pressure, the magnitude of the depressed ERG and optic tract responses were linearly related to the perfusion pressure. The maximum effect occurred within 5 min, and after the intraocular pressure was restored to normal, the optic tract response and ERG returned to normal in 4 to 5 min. It is not clear whether the phenomena studied here have any relationship to the optic nerve damage seen in chronic open angle glaucoma, where the perfusion pressure is usually greater than 30 mm Hg.

Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalArchives of Ophthalmology
Volume90
Issue number2
StatePublished - Dec 1 1973

Fingerprint

Aotidae
Neural Conduction
Optic Nerve
Intraocular Pressure
Pressure
Perfusion
Open Angle Glaucoma
Thigh
Blood Pressure
Optic Tract

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Pressure effect on ERG and optic nerve conduction of visual impulse : short term effects in owl monkeys. / Gerstle, C. L.; Anderson, Douglas; Hamasaki, D. I.

In: Archives of Ophthalmology, Vol. 90, No. 2, 01.12.1973, p. 121-124.

Research output: Contribution to journalArticle

Gerstle, C. L. ; Anderson, Douglas ; Hamasaki, D. I. / Pressure effect on ERG and optic nerve conduction of visual impulse : short term effects in owl monkeys. In: Archives of Ophthalmology. 1973 ; Vol. 90, No. 2. pp. 121-124.
@article{d72f4ed94f5d43a5a38d7069cf289741,
title = "Pressure effect on ERG and optic nerve conduction of visual impulse: short term effects in owl monkeys",
abstract = "The effects of increased intraocular pressure on optic tract responses and the electroretinogram (ERG) b wave were studied in owl monkeys. Both responses showed a decrease in amplitude only if the intraocular pressures exceeded a certain critical level, which was about 30 mm Hg below mean femoral blood pressure. Above this intraocular pressure, the magnitude of the depressed ERG and optic tract responses were linearly related to the perfusion pressure. The maximum effect occurred within 5 min, and after the intraocular pressure was restored to normal, the optic tract response and ERG returned to normal in 4 to 5 min. It is not clear whether the phenomena studied here have any relationship to the optic nerve damage seen in chronic open angle glaucoma, where the perfusion pressure is usually greater than 30 mm Hg.",
author = "Gerstle, {C. L.} and Douglas Anderson and Hamasaki, {D. I.}",
year = "1973",
month = "12",
day = "1",
language = "English",
volume = "90",
pages = "121--124",
journal = "JAMA Ophthalmology",
issn = "2168-6165",
publisher = "American Medical Association",
number = "2",

}

TY - JOUR

T1 - Pressure effect on ERG and optic nerve conduction of visual impulse

T2 - short term effects in owl monkeys

AU - Gerstle, C. L.

AU - Anderson, Douglas

AU - Hamasaki, D. I.

PY - 1973/12/1

Y1 - 1973/12/1

N2 - The effects of increased intraocular pressure on optic tract responses and the electroretinogram (ERG) b wave were studied in owl monkeys. Both responses showed a decrease in amplitude only if the intraocular pressures exceeded a certain critical level, which was about 30 mm Hg below mean femoral blood pressure. Above this intraocular pressure, the magnitude of the depressed ERG and optic tract responses were linearly related to the perfusion pressure. The maximum effect occurred within 5 min, and after the intraocular pressure was restored to normal, the optic tract response and ERG returned to normal in 4 to 5 min. It is not clear whether the phenomena studied here have any relationship to the optic nerve damage seen in chronic open angle glaucoma, where the perfusion pressure is usually greater than 30 mm Hg.

AB - The effects of increased intraocular pressure on optic tract responses and the electroretinogram (ERG) b wave were studied in owl monkeys. Both responses showed a decrease in amplitude only if the intraocular pressures exceeded a certain critical level, which was about 30 mm Hg below mean femoral blood pressure. Above this intraocular pressure, the magnitude of the depressed ERG and optic tract responses were linearly related to the perfusion pressure. The maximum effect occurred within 5 min, and after the intraocular pressure was restored to normal, the optic tract response and ERG returned to normal in 4 to 5 min. It is not clear whether the phenomena studied here have any relationship to the optic nerve damage seen in chronic open angle glaucoma, where the perfusion pressure is usually greater than 30 mm Hg.

UR - http://www.scopus.com/inward/record.url?scp=0015850252&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0015850252&partnerID=8YFLogxK

M3 - Article

C2 - 4198464

AN - SCOPUS:0015850252

VL - 90

SP - 121

EP - 124

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

SN - 2168-6165

IS - 2

ER -